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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HPS1 All Species: 20.61
Human Site: T155 Identified Species: 50.37
UniProt: Q92902 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92902 NP_000186.2 700 79292 T155 H F Q S L L W T Y S R L R E Q
Chimpanzee Pan troglodytes XP_001165998 700 79247 T155 H F Q S L L W T Y S R L R E Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534985 701 79233 T155 H F Q S L L W T Y G R L R E Q
Cat Felis silvestris
Mouse Mus musculus O08983 704 79835 T155 H F Q R L L G T Y S Y L R D R
Rat Rattus norvegicus NP_414541 706 80241 T155 H F Q R L L G T Y S R L R E Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508131 674 76268 C145 R L I H P Q L C E Q C I E I L
Chicken Gallus gallus NP_001026751 702 79129 T151 L L R G L L E T Y I C L R E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001032777 668 77052 L144 D T E Q R N R L W K K L R S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610997 596 66684 M105 V E L L G R Q M G V A I T L T
Honey Bee Apis mellifera XP_001121837 556 63548 S65 N I I M Q L F S P I V T S Q H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 84.4 N.A. 80.8 81.7 N.A. 70.1 62.6 N.A. 54 N.A. 25 20.5 N.A. N.A.
Protein Similarity: 100 100 N.A. 91.4 N.A. 88.6 88.9 N.A. 81.4 76.7 N.A. 70.7 N.A. 43.4 37.2 N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 66.6 86.6 N.A. 0 46.6 N.A. 13.3 N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 80 86.6 N.A. 6.6 60 N.A. 33.3 N.A. 6.6 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 20 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 0 10 10 0 0 0 10 0 10 0 0 0 10 50 10 % E
% Phe: 0 50 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 10 0 20 0 10 10 0 0 0 0 0 % G
% His: 50 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 10 20 0 0 0 0 0 0 20 0 20 0 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % K
% Leu: 10 20 10 10 60 70 10 10 0 0 0 70 0 10 20 % L
% Met: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 50 10 10 10 10 0 0 10 0 0 0 10 40 % Q
% Arg: 10 0 10 20 10 10 10 0 0 0 40 0 70 0 10 % R
% Ser: 0 0 0 30 0 0 0 10 0 40 0 0 10 10 0 % S
% Thr: 0 10 0 0 0 0 0 60 0 0 0 10 10 0 10 % T
% Val: 10 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 30 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 60 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _