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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDS1 All Species: 31.52
Human Site: S77 Identified Species: 57.78
UniProt: Q92903 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92903 NP_001254.2 461 53304 S77 E I L K K A L S G L S S R W K
Chimpanzee Pan troglodytes XP_517179 461 53272 S77 E I L K K A L S G L S S R W K
Rhesus Macaque Macaca mulatta XP_001104375 460 52839 S77 E I L K K A L S G L S S R Y D
Dog Lupus familis XP_544962 461 52992 S77 E I L K K A L S G L S S R W K
Cat Felis silvestris
Mouse Mus musculus P98191 461 52857 S77 E I L K K A L S G L S S R W K
Rat Rattus norvegicus O35052 461 52951 S77 E I L K K A L S G L S S R W K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513442 748 84077 S174 E I L K R A L S G L S S R W K
Chicken Gallus gallus XP_420571 537 60927 S153 E I L K R A L S G L S A R W K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341899 452 51974 W76 S S R W K N W W I R G I L S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P56079 447 51493 L76 L D S A L K D L P D R W K N W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P53439 455 52423 E76 V F A D S M L E A L P P R W R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04928 421 48641 F49 D R N K Y K S F M V R T Y S T
Baker's Yeast Sacchar. cerevisiae P38221 457 51804 F76 T F V M I S G F F I T L A S G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 93.4 97.1 N.A. 95.8 95.4 N.A. 54.8 71.6 N.A. 75 N.A. 55.9 N.A. 50.9 N.A.
Protein Similarity: 100 99.5 96.9 98.2 N.A. 97.6 97.1 N.A. 57.7 78 N.A. 84.1 N.A. 71.3 N.A. 65.5 N.A.
P-Site Identity: 100 100 86.6 100 N.A. 100 100 N.A. 93.3 86.6 N.A. 6.6 N.A. 0 N.A. 26.6 N.A.
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 100 100 N.A. 6.6 N.A. 6.6 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.7 38.6 N.A.
Protein Similarity: N.A. N.A. N.A. 55.7 55.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 62 0 0 8 0 0 8 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 8 0 0 8 0 0 8 0 0 0 0 8 % D
% Glu: 62 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 16 0 0 0 0 0 16 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 62 0 8 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 62 0 0 8 0 0 0 8 8 0 8 0 0 0 % I
% Lys: 0 0 0 70 54 16 0 0 0 0 0 0 8 0 54 % K
% Leu: 8 0 62 0 8 0 70 8 0 70 0 8 8 0 8 % L
% Met: 0 0 0 8 0 8 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 8 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 8 0 16 0 0 0 0 8 16 0 70 0 8 % R
% Ser: 8 8 8 0 8 8 8 62 0 0 62 54 0 24 0 % S
% Thr: 8 0 0 0 0 0 0 0 0 0 8 8 0 0 8 % T
% Val: 8 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 8 0 0 8 8 0 0 0 8 0 62 8 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _