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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDS1 All Species: 35.45
Human Site: Y137 Identified Species: 65
UniProt: Q92903 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92903 NP_001254.2 461 53304 Y137 G Y R V Y H S Y D L P W F R T
Chimpanzee Pan troglodytes XP_517179 461 53272 Y137 G Y R V Y H S Y D L P W F R T
Rhesus Macaque Macaca mulatta XP_001104375 460 52839 Y136 G Y R V Y H S Y D L P W F R T
Dog Lupus familis XP_544962 461 52992 Y137 G Y R V Y R S Y D L P W F R T
Cat Felis silvestris
Mouse Mus musculus P98191 461 52857 Y137 G Y R V Y H S Y D L P W F R T
Rat Rattus norvegicus O35052 461 52951 Y137 G Y R V Y H S Y D L P W F R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513442 748 84077 Y234 G Y R V Y H S Y D L P W F R T
Chicken Gallus gallus XP_420571 537 60927 Y213 G Y R V Y H S Y D L P W F R S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341899 452 51974 R132 S Y E L P W F R T L S W Y F L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P56079 447 51493 Y131 I S I G Y Q V Y R I H G L P W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P53439 455 52423 Y136 G L A V Y R L Y D F P W F R A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04928 421 48641 Y104 P E D K C L P Y I K Q L N W H
Baker's Yeast Sacchar. cerevisiae P38221 457 51804 K136 T I Y Y L D G K S L F K F F Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 93.4 97.1 N.A. 95.8 95.4 N.A. 54.8 71.6 N.A. 75 N.A. 55.9 N.A. 50.9 N.A.
Protein Similarity: 100 99.5 96.9 98.2 N.A. 97.6 97.1 N.A. 57.7 78 N.A. 84.1 N.A. 71.3 N.A. 65.5 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 100 93.3 N.A. 20 N.A. 13.3 N.A. 60 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 100 100 N.A. 33.3 N.A. 20 N.A. 60 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.7 38.6 N.A.
Protein Similarity: N.A. N.A. N.A. 55.7 55.9 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 8 0 0 70 0 0 0 0 0 0 % D
% Glu: 0 8 8 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 8 8 0 77 16 0 % F
% Gly: 70 0 0 8 0 0 8 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 0 0 54 0 0 0 0 8 0 0 0 8 % H
% Ile: 8 8 8 0 0 0 0 0 8 8 0 0 0 0 0 % I
% Lys: 0 0 0 8 0 0 0 8 0 8 0 8 0 0 0 % K
% Leu: 0 8 0 8 8 8 8 0 0 77 0 8 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 8 0 0 0 8 0 8 0 0 0 70 0 0 8 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 8 0 0 0 8 % Q
% Arg: 0 0 62 0 0 16 0 8 8 0 0 0 0 70 0 % R
% Ser: 8 8 0 0 0 0 62 0 8 0 8 0 0 0 8 % S
% Thr: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 54 % T
% Val: 0 0 0 70 0 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 77 0 8 8 % W
% Tyr: 0 70 8 8 77 0 0 85 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _