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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DAZL All Species: 34.85
Human Site: S257 Identified Species: 69.7
UniProt: Q92904 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92904 NP_001342.2 295 33178 S257 R S I Q T V V S C L F N P E N
Chimpanzee Pan troglodytes XP_516314 410 44775 S372 R G I Q T V V S C L F N P E N
Rhesus Macaque Macaca mulatta XP_001084406 295 33096 S257 R S I Q T V V S C L F N P E N
Dog Lupus familis XP_534251 455 49965 S400 R S I Q T V V S C L F N P E N
Cat Felis silvestris
Mouse Mus musculus Q64368 298 33294 S257 R S I Q T V V S C L F N P E N
Rat Rattus norvegicus NP_001102884 281 31359 S240 R S I Q T V V S C L F N P E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514729 390 42895 S352 R S I Q T V V S C L L N P D N
Chicken Gallus gallus Q804A9 289 32698 S251 R S I Q T V V S C L F N P E N
Frog Xenopus laevis Q4V7Y4 286 32292 S247 M S T Q T I V S C L F D P A N
Zebra Danio Brachydanio rerio Q9YGW7 229 25529 Q192 Q V P M N Y A Q T T Y A Y Q Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24207 228 24663 H191 P Q N Y Q E N H S P L L H S P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20870 499 56134 P450 Q D K K T K S P I K G A R T E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.7 98.3 58 N.A. 87.2 83 N.A. 59.2 68.8 56.6 36.6 N.A. 25 N.A. 23.4 N.A.
Protein Similarity: 100 71.7 98.9 61 N.A. 93.2 88.8 N.A. 66.6 81.3 72.8 47.1 N.A. 39.3 N.A. 36.2 N.A.
P-Site Identity: 100 93.3 100 100 N.A. 100 100 N.A. 86.6 100 66.6 0 N.A. 0 N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 93.3 100 80 20 N.A. 0 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 0 0 0 0 17 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 75 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 9 0 9 0 % D
% Glu: 0 0 0 0 0 9 0 0 0 0 0 0 0 59 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 0 % H
% Ile: 0 0 67 0 0 9 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 9 9 0 9 0 0 0 9 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 75 17 9 0 0 0 % L
% Met: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 9 0 9 0 0 0 0 67 0 0 75 % N
% Pro: 9 0 9 0 0 0 0 9 0 9 0 0 75 0 9 % P
% Gln: 17 9 0 75 9 0 0 9 0 0 0 0 0 9 0 % Q
% Arg: 67 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 67 0 0 0 0 9 75 9 0 0 0 0 9 0 % S
% Thr: 0 0 9 0 84 0 0 0 9 9 0 0 0 9 0 % T
% Val: 0 9 0 0 0 67 75 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 9 0 0 0 0 9 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _