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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPKOW
All Species:
8.48
Human Site:
S146
Identified Species:
18.67
UniProt:
Q92917
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92917
NP_056513.2
476
52229
S146
P
S
G
E
G
A
D
S
E
P
R
A
E
T
V
Chimpanzee
Pan troglodytes
XP_001141772
224
23867
Rhesus Macaque
Macaca mulatta
XP_001105674
498
55226
G168
E
S
A
L
M
N
L
G
G
R
R
L
A
R
V
Dog
Lupus familis
XP_538033
484
53417
S146
P
N
G
E
G
A
D
S
E
P
R
A
E
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q56A08
488
53813
S146
P
I
E
E
G
S
D
S
E
P
Q
A
E
T
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507594
502
55083
G193
V
P
D
G
F
E
D
G
D
K
V
D
V
S
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU07
487
54677
V135
G
Y
E
D
R
E
K
V
D
V
S
L
R
P
D
Zebra Danio
Brachydanio rerio
Q90X38
506
57936
N158
F
E
D
G
D
K
V
N
V
D
L
R
P
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623528
264
29888
Nematode Worm
Caenorhab. elegans
Q21924
462
51694
V136
S
G
K
G
E
K
I
V
V
E
D
G
R
G
D
Sea Urchin
Strong. purpuratus
XP_780912
479
55253
I133
A
N
Y
E
E
V
P
I
E
Q
F
G
M
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.8
68.4
80.7
N.A.
74.3
N.A.
N.A.
43.4
N.A.
45.7
44
N.A.
N.A.
24.1
26.2
32.3
Protein Similarity:
100
38.4
73.4
88.6
N.A.
82.5
N.A.
N.A.
56.3
N.A.
61.5
59.2
N.A.
N.A.
39.7
47
53.4
P-Site Identity:
100
0
20
93.3
N.A.
73.3
N.A.
N.A.
6.6
N.A.
0
0
N.A.
N.A.
0
0
13.3
P-Site Similarity:
100
0
20
100
N.A.
86.6
N.A.
N.A.
26.6
N.A.
13.3
6.6
N.A.
N.A.
0
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
19
0
0
0
0
0
28
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
10
10
0
37
0
19
10
10
10
0
0
19
% D
% Glu:
10
10
19
37
19
19
0
0
37
10
0
0
28
10
0
% E
% Phe:
10
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
10
10
19
28
28
0
0
19
10
0
0
19
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
19
10
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
10
0
0
0
10
19
0
0
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
10
% M
% Asn:
0
19
0
0
0
10
0
10
0
0
0
0
0
0
0
% N
% Pro:
28
10
0
0
0
0
10
0
0
28
0
0
10
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
10
28
10
19
10
0
% R
% Ser:
10
19
0
0
0
10
0
28
0
0
10
0
0
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% T
% Val:
10
0
0
0
0
10
10
19
19
10
10
0
10
0
37
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _