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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP4K1
All Species:
15.76
Human Site:
S270
Identified Species:
31.52
UniProt:
Q92918
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92918
NP_009112.1
833
91296
S270
P
S
A
T
K
M
L
S
H
Q
L
V
S
Q
P
Chimpanzee
Pan troglodytes
XP_522848
845
94894
T273
P
T
A
E
R
L
L
T
H
T
F
V
A
Q
P
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
Dog
Lupus familis
XP_541641
821
90630
S270
P
C
A
T
K
M
L
S
H
Q
L
V
S
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
P70218
827
91516
S270
P
S
A
T
K
M
L
S
H
Q
L
V
S
Q
P
Rat
Rattus norvegicus
Q924I2
873
98660
Q269
P
T
A
E
K
L
L
Q
H
P
F
V
T
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515144
898
100018
T325
P
T
A
E
R
L
L
T
H
N
F
V
G
Q
P
Chicken
Gallus gallus
Q5ZJK4
486
55318
Frog
Xenopus laevis
Q6IP06
493
56486
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8T0S6
669
75091
L177
N
T
E
G
Y
A
K
L
A
D
F
G
V
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23356
1096
122486
R284
P
Y
T
G
A
L
L
R
H
P
F
I
K
E
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.5
25.2
89.8
N.A.
83
44.6
N.A.
42.4
25.5
24
24.6
N.A.
25.5
N.A.
23.8
N.A.
Protein Similarity:
100
61.8
40
93.4
N.A.
89.8
61.5
N.A.
58.3
39.8
39.8
39.7
N.A.
44
N.A.
40.2
N.A.
P-Site Identity:
100
46.6
0
93.3
N.A.
100
53.3
N.A.
46.6
0
0
0
N.A.
0
N.A.
20
N.A.
P-Site Similarity:
100
80
0
93.3
N.A.
100
73.3
N.A.
73.3
0
0
0
N.A.
6.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
9
9
0
0
9
0
0
0
9
9
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
9
25
0
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
42
0
0
0
0
% F
% Gly:
0
0
0
17
0
0
0
0
0
0
0
9
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
0
0
0
34
0
9
0
0
0
0
0
9
0
0
% K
% Leu:
0
0
0
0
0
34
59
9
0
0
25
0
0
0
0
% L
% Met:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
59
0
0
0
0
0
0
0
0
17
0
0
0
0
50
% P
% Gln:
0
0
0
0
0
0
0
9
0
25
0
0
0
50
9
% Q
% Arg:
0
0
0
0
17
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
17
0
0
0
0
0
25
0
0
0
0
25
0
0
% S
% Thr:
0
34
9
25
0
0
0
17
0
9
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
50
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _