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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXTL1
All Species:
9.39
Human Site:
S460
Identified Species:
20.67
UniProt:
Q92935
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92935
NP_004446.2
676
74697
S460
S
N
E
R
P
L
P
S
R
W
P
E
T
A
V
Chimpanzee
Pan troglodytes
XP_001138068
663
73293
S460
S
N
E
R
P
L
P
S
R
W
P
E
T
A
V
Rhesus Macaque
Macaca mulatta
XP_001108202
675
74245
S459
S
N
E
R
P
L
P
S
S
W
P
E
T
A
M
Dog
Lupus familis
XP_544489
672
73803
P459
S
S
E
K
P
L
P
P
R
W
P
K
T
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKV7
669
73991
D453
N
S
E
K
P
P
P
D
R
W
P
E
T
A
V
Rat
Rattus norvegicus
NP_001101455
670
74649
D454
N
S
E
K
P
P
P
D
R
W
P
K
T
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418396
865
98072
R647
K
P
L
P
A
K
H
R
W
P
A
T
S
V
P
Frog
Xenopus laevis
NP_001083782
738
84810
R520
K
P
L
P
A
K
H
R
W
P
A
T
T
V
P
Zebra Danio
Brachydanio rerio
Q5IGR8
730
84599
R512
K
P
L
P
S
K
H
R
W
P
A
T
S
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V730
760
87290
T544
V
I
S
L
G
G
S
T
R
S
Q
G
A
G
P
Honey Bee
Apis mellifera
XP_391845
711
82974
R493
S
D
I
P
L
P
R
R
P
R
W
Q
G
I
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
96
80
N.A.
73.9
73.8
N.A.
N.A.
41.2
46.3
44.3
N.A.
38
38.8
N.A.
N.A.
Protein Similarity:
100
97.4
97.9
85
N.A.
81.3
82.2
N.A.
N.A.
53.9
60.9
60.1
N.A.
54.3
56.6
N.A.
N.A.
P-Site Identity:
100
100
86.6
66.6
N.A.
66.6
60
N.A.
N.A.
0
6.6
0
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
19
0
0
0
0
0
28
0
10
46
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
19
0
0
0
0
0
0
0
% D
% Glu:
0
0
55
0
0
0
0
0
0
0
0
37
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
0
0
0
10
10
10
0
% G
% His:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
28
0
0
28
0
28
0
0
0
0
0
19
0
0
10
% K
% Leu:
0
0
28
10
10
37
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
19
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
28
0
37
55
28
55
10
10
28
55
0
0
0
37
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% Q
% Arg:
0
0
0
28
0
0
10
37
55
10
0
0
0
0
0
% R
% Ser:
46
28
10
0
10
0
10
28
10
10
0
0
19
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
28
64
10
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
0
0
0
28
46
% V
% Trp:
0
0
0
0
0
0
0
0
28
55
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _