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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GCDH
All Species:
17.58
Human Site:
Y197
Identified Species:
32.22
UniProt:
Q92947
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92947
NP_000150.1
438
48127
Y197
S
M
E
T
R
A
H
Y
N
S
S
N
K
S
Y
Chimpanzee
Pan troglodytes
A5A6I0
421
46589
K197
M
W
I
T
N
G
G
K
A
N
W
Y
F
L
L
Rhesus Macaque
Macaca mulatta
XP_001110384
438
48283
Y197
S
M
E
T
R
A
R
Y
N
S
S
N
K
S
Y
Dog
Lupus familis
XP_533901
438
48206
H197
S
M
E
T
R
A
R
H
N
P
S
N
R
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q60759
438
48628
H197
G
M
E
T
R
A
R
H
N
P
S
N
Q
S
Y
Rat
Rattus norvegicus
P15651
412
44747
S189
T
K
A
W
I
T
N
S
W
E
A
S
A
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510278
489
53688
H248
S
M
E
T
R
A
R
H
N
S
A
N
K
T
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086623
440
48380
Y199
G
M
E
T
R
A
R
Y
N
P
S
S
K
T
Y
Zebra Danio
Brachydanio rerio
NP_957180
441
48867
Y200
G
M
E
T
K
A
K
Y
N
P
S
S
R
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSA3
419
45853
A194
W
I
T
N
G
G
V
A
N
W
Y
F
V
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20772
409
44946
S186
N
G
S
K
T
W
I
S
N
S
P
V
S
D
V
Sea Urchin
Strong. purpuratus
XP_785958
444
48552
Y201
G
M
E
T
K
A
V
Y
N
P
S
S
K
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96329
436
47538
K192
G
L
G
T
T
A
T
K
V
E
G
G
W
K
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28
98.1
89.7
N.A.
85.8
29.6
N.A.
71.9
N.A.
74.5
73
N.A.
31
N.A.
58.9
70.2
Protein Similarity:
100
46.3
99
94.7
N.A.
90.8
47.7
N.A.
80.7
N.A.
86.8
86.3
N.A.
48.1
N.A.
73.2
82.6
P-Site Identity:
100
6.6
93.3
73.3
N.A.
66.6
0
N.A.
66.6
N.A.
66.6
53.3
N.A.
6.6
N.A.
13.3
60
P-Site Similarity:
100
13.3
93.3
86.6
N.A.
80
33.3
N.A.
93.3
N.A.
80
80
N.A.
13.3
N.A.
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
70
0
8
8
0
16
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
62
0
0
0
0
0
0
16
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
8
% F
% Gly:
39
8
8
0
8
16
8
0
0
0
8
8
0
0
0
% G
% His:
0
0
0
0
0
0
8
24
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
0
8
0
0
0
0
0
0
0
8
% I
% Lys:
0
8
0
8
16
0
8
16
0
0
0
0
39
8
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
0
16
8
% L
% Met:
8
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
8
0
8
0
77
8
0
39
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
39
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
47
0
39
0
0
0
0
0
16
0
0
% R
% Ser:
31
0
8
0
0
0
0
16
0
31
54
31
8
31
0
% S
% Thr:
8
0
8
77
16
8
8
0
0
0
0
0
0
39
0
% T
% Val:
0
0
0
0
0
0
16
0
8
0
0
8
8
0
16
% V
% Trp:
8
8
0
8
0
8
0
0
8
8
8
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
8
8
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _