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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNN1 All Species: 8.48
Human Site: T535 Identified Species: 18.67
UniProt: Q92952 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92952 NP_002239.2 543 59987 T535 R S S P C R W T P V A P S D C
Chimpanzee Pan troglodytes XP_001173769 626 68407 T618 R S S P C R W T P V A P S D C
Rhesus Macaque Macaca mulatta XP_001115129 505 55610 S495 M E Q P R E G S V L V L N K A
Dog Lupus familis XP_541945 579 63686 P571 R S P P C Q W P P M A P S D C
Cat Felis silvestris
Mouse Mus musculus Q9EQR3 537 59311 L529 H S P Q S H W L P T M G S D C
Rat Rattus norvegicus P70606 536 59196 L528 Q S P Q S H W L P T T A S D C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514810 524 58170 K511 W T P T R R R K S P S T A P H
Chicken Gallus gallus NP_990129 553 61999 A545 R R R S S S T A P P T S S E S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001121720 538 60476 S526 T P S R R R R S P S T A P H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KVW5 924 101426 T908 V A P I Q A P T P Q S M F N A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q11122 471 54319 E463 D E M R M Q I E V V K F V L K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 83.7 88 N.A. 83.4 83.7 N.A. 66.6 69.4 N.A. 74.9 N.A. 37.2 N.A. 29.1 N.A.
Protein Similarity: 100 86.7 84.3 90.5 N.A. 88.7 88.4 N.A. 74.4 78.3 N.A. 81.4 N.A. 45.5 N.A. 46.9 N.A.
P-Site Identity: 100 100 6.6 73.3 N.A. 40 40 N.A. 6.6 20 N.A. 20 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 26.6 86.6 N.A. 40 46.6 N.A. 26.6 26.6 N.A. 26.6 N.A. 33.3 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 10 0 10 0 0 28 19 10 0 19 % A
% Cys: 0 0 0 0 28 0 0 0 0 0 0 0 0 0 46 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 46 0 % D
% Glu: 0 19 0 0 0 10 0 10 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % G
% His: 10 0 0 0 0 19 0 0 0 0 0 0 0 10 10 % H
% Ile: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 10 0 0 10 10 % K
% Leu: 0 0 0 0 0 0 0 19 0 10 0 10 0 10 0 % L
% Met: 10 0 10 0 10 0 0 0 0 10 10 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % N
% Pro: 0 10 46 37 0 0 10 10 73 19 0 28 10 10 0 % P
% Gln: 10 0 10 19 10 19 0 0 0 10 0 0 0 0 0 % Q
% Arg: 37 10 10 19 28 37 19 0 0 0 0 0 0 0 0 % R
% Ser: 0 46 28 10 28 10 0 19 10 10 19 10 55 0 10 % S
% Thr: 10 10 0 10 0 0 10 28 0 19 28 10 0 0 10 % T
% Val: 10 0 0 0 0 0 0 0 19 28 10 0 10 0 0 % V
% Trp: 10 0 0 0 0 0 46 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _