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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNPO1 All Species: 16.67
Human Site: S30 Identified Species: 30.56
UniProt: Q92973 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92973 NP_002261.3 898 102355 S30 I L Q L L K E S Q S P D T T I
Chimpanzee Pan troglodytes XP_512411 1060 118770 S193 V L Q L L K D S Q S P N T A T
Rhesus Macaque Macaca mulatta XP_001095625 862 98044 D26 L K E S Q S P D T T I Q R T V
Dog Lupus familis XP_535270 925 104519 R57 C R F C M G L R L N N K G R S
Cat Felis silvestris
Mouse Mus musculus Q8BFY9 898 102339 S30 I L Q L L K E S Q S P D T T I
Rat Rattus norvegicus XP_001070389 895 101848 S27 I L Q L L K E S Q S P D T T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512908 879 99027 A27 S V Q H P F T A N V A T K L E
Chicken Gallus gallus XP_424806 890 101281 D26 L K E S Q S P D T T T Q R A V
Frog Xenopus laevis NP_001088603 890 101114 D26 L K E S Q S P D N N T Q R A V
Zebra Danio Brachydanio rerio XP_691079 891 101212 D26 L K E S Q S P D T S T Q R S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477368 893 101498 A26 E S Q S P D T A T Q M A V Q M
Honey Bee Apis mellifera XP_392373 933 105655 S56 I L T L L K E S Q S P D T A T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38217 918 103663 A33 N P E I R N N A M E A M E N F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.2 95.6 93 N.A. 99.6 98.8 N.A. 91.1 95.8 93.6 91.8 N.A. 73.7 75.4 N.A. N.A.
Protein Similarity: 100 79.2 95.9 94.8 N.A. 99.8 99.3 N.A. 92.8 97.5 96.5 96.3 N.A. 85.1 86.3 N.A. N.A.
P-Site Identity: 100 66.6 6.6 0 N.A. 100 100 N.A. 6.6 0 0 6.6 N.A. 6.6 80 N.A. N.A.
P-Site Similarity: 100 86.6 33.3 13.3 N.A. 100 100 N.A. 20 26.6 26.6 33.3 N.A. 20 80 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 55.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 24 0 0 16 8 0 31 0 % A
% Cys: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 8 31 0 0 0 31 0 0 0 % D
% Glu: 8 0 39 0 0 0 31 0 0 8 0 0 8 0 8 % E
% Phe: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 31 0 0 8 0 0 0 0 0 0 8 0 0 0 24 % I
% Lys: 0 31 0 0 0 39 0 0 0 0 0 8 8 0 0 % K
% Leu: 31 39 0 39 39 0 8 0 8 0 0 0 0 8 0 % L
% Met: 0 0 0 0 8 0 0 0 8 0 8 8 0 0 8 % M
% Asn: 8 0 0 0 0 8 8 0 16 16 8 8 0 8 0 % N
% Pro: 0 8 0 0 16 0 31 0 0 0 39 0 0 0 0 % P
% Gln: 0 0 47 0 31 0 0 0 39 8 0 31 0 8 0 % Q
% Arg: 0 8 0 0 8 0 0 8 0 0 0 0 31 8 0 % R
% Ser: 8 8 0 39 0 31 0 39 0 47 0 0 0 8 8 % S
% Thr: 0 0 8 0 0 0 16 0 31 16 24 8 39 31 16 % T
% Val: 8 8 0 0 0 0 0 0 0 8 0 0 8 0 31 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _