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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNPO1
All Species:
45.15
Human Site:
S464
Identified Species:
82.78
UniProt:
Q92973
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92973
NP_002261.3
898
102355
S464
D
K
K
A
L
V
R
S
I
T
C
W
T
L
S
Chimpanzee
Pan troglodytes
XP_512411
1060
118770
S626
D
K
K
A
L
V
R
S
I
A
C
W
T
L
S
Rhesus Macaque
Macaca mulatta
XP_001095625
862
98044
S456
D
K
K
A
L
V
R
S
I
T
C
W
T
L
S
Dog
Lupus familis
XP_535270
925
104519
S491
D
K
K
A
L
V
R
S
I
T
C
W
T
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFY9
898
102339
S464
D
K
K
A
L
V
R
S
I
T
C
W
T
L
S
Rat
Rattus norvegicus
XP_001070389
895
101848
S461
D
K
K
A
L
V
R
S
I
T
C
W
T
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512908
879
99027
S452
D
K
K
A
L
V
R
S
I
T
C
W
T
L
S
Chicken
Gallus gallus
XP_424806
890
101281
S456
D
K
K
A
L
V
R
S
I
T
C
W
T
L
S
Frog
Xenopus laevis
NP_001088603
890
101114
S456
D
K
K
A
L
V
R
S
I
T
C
W
T
L
S
Zebra Danio
Brachydanio rerio
XP_691079
891
101212
S457
D
K
K
A
L
V
R
S
I
T
C
W
T
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477368
893
101498
S460
D
K
K
A
L
V
R
S
I
T
C
W
T
L
S
Honey Bee
Apis mellifera
XP_392373
933
105655
A499
D
K
K
A
L
V
R
A
I
T
C
W
T
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38217
918
103663
K480
D
K
W
A
P
V
R
K
M
T
C
W
T
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.2
95.6
93
N.A.
99.6
98.8
N.A.
91.1
95.8
93.6
91.8
N.A.
73.7
75.4
N.A.
N.A.
Protein Similarity:
100
79.2
95.9
94.8
N.A.
99.8
99.3
N.A.
92.8
97.5
96.5
96.3
N.A.
85.1
86.3
N.A.
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
100
100
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
100
0
0
0
8
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% C
% Asp:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
93
0
0
0
0
0
0
% I
% Lys:
0
100
93
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
93
0
0
0
0
0
0
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
85
0
0
0
0
0
0
100
% S
% Thr:
0
0
0
0
0
0
0
0
0
93
0
0
100
0
0
% T
% Val:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
100
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _