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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TNPO1 All Species: 50
Human Site: Y612 Identified Species: 91.67
UniProt: Q92973 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92973 NP_002261.3 898 102355 Y612 L Q S G F L P Y C E P V Y Q R
Chimpanzee Pan troglodytes XP_512411 1060 118770 Y774 L Q S G F L P Y C E P V Y Q R
Rhesus Macaque Macaca mulatta XP_001095625 862 98044 Y604 L Q S G F L P Y C E P V Y Q R
Dog Lupus familis XP_535270 925 104519 Y639 L Q S G F L P Y C E P V Y Q R
Cat Felis silvestris
Mouse Mus musculus Q8BFY9 898 102339 Y612 L Q S G F L P Y C E P V Y Q R
Rat Rattus norvegicus XP_001070389 895 101848 Y609 L Q S G F L P Y C E P V Y Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512908 879 99027 Y600 L Q S G F L P Y C E P V Y Q R
Chicken Gallus gallus XP_424806 890 101281 Y604 L Q S G F L P Y C E P V Y Q R
Frog Xenopus laevis NP_001088603 890 101114 Y604 L Q S G F L P Y C E P V Y Q R
Zebra Danio Brachydanio rerio XP_691079 891 101212 Y605 L Q S G F L P Y C E P V Y Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477368 893 101498 Y608 L Q S G F L P Y C D P V Y R R
Honey Bee Apis mellifera XP_392373 933 105655 Y647 L R S G F L P Y C E P V Y R R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38217 918 103663 M626 L G E R F M P M A P E V Y N R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.2 95.6 93 N.A. 99.6 98.8 N.A. 91.1 95.8 93.6 91.8 N.A. 73.7 75.4 N.A. N.A.
Protein Similarity: 100 79.2 95.9 94.8 N.A. 99.8 99.3 N.A. 92.8 97.5 96.5 96.3 N.A. 85.1 86.3 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 86.6 86.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 100 100 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 55.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 93 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 85 8 0 0 0 0 % E
% Phe: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 93 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 100 0 0 0 0 93 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 100 0 0 8 93 0 0 0 0 % P
% Gln: 0 85 0 0 0 0 0 0 0 0 0 0 0 77 0 % Q
% Arg: 0 8 0 8 0 0 0 0 0 0 0 0 0 16 100 % R
% Ser: 0 0 93 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 93 0 0 0 0 100 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _