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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF7
All Species:
0.91
Human Site:
T391
Identified Species:
2.22
UniProt:
Q92985
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92985
NP_001563.2
503
54278
T391
P
G
S
A
S
P
S
T
P
A
C
L
L
P
R
Chimpanzee
Pan troglodytes
XP_001147267
439
48559
N335
P
A
C
L
L
P
R
N
C
D
T
P
I
F
D
Rhesus Macaque
Macaca mulatta
XP_001092569
500
56291
N361
S
A
H
D
S
C
P
N
P
I
Q
R
E
V
K
Dog
Lupus familis
XP_540526
284
31613
T190
T
P
I
F
D
F
S
T
F
F
R
E
M
A
E
Cat
Felis silvestris
Mouse
Mus musculus
P70434
457
51203
E351
S
T
P
P
Q
L
L
E
R
N
R
H
T
P
I
Rat
Rattus norvegicus
NP_001028863
455
50697
N351
P
A
Q
L
L
E
R
N
C
H
T
P
I
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508806
462
52633
I366
E
K
Q
P
P
F
E
I
Y
F
C
F
G
E
E
Chicken
Gallus gallus
Q90643
491
54423
P382
Q
Q
L
E
G
G
E
P
P
L
N
L
L
H
R
Frog
Xenopus laevis
NP_001079588
466
52659
Q355
P
E
I
S
Q
P
N
Q
I
D
K
N
D
Y
C
Zebra Danio
Brachydanio rerio
NP_956971
423
49042
L329
Q
N
Y
K
E
Q
L
L
S
F
D
K
Y
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.7
28.2
43.7
N.A.
62.6
63.8
N.A.
28
41.5
25.8
31.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
82.5
41.9
48.5
N.A.
69.5
70.9
N.A.
43.1
53.2
43.3
46.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
13.3
13.3
N.A.
6.6
6.6
N.A.
6.6
26.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
20
N.A.
6.6
13.3
N.A.
6.6
26.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
10
0
0
0
0
0
10
0
0
0
10
0
% A
% Cys:
0
0
10
0
0
10
0
0
20
0
20
0
0
0
10
% C
% Asp:
0
0
0
10
10
0
0
0
0
20
10
0
10
0
20
% D
% Glu:
10
10
0
10
10
10
20
10
0
0
0
10
10
10
20
% E
% Phe:
0
0
0
10
0
20
0
0
10
30
0
10
0
20
0
% F
% Gly:
0
10
0
0
10
10
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
10
0
10
0
10
0
% H
% Ile:
0
0
20
0
0
0
0
10
10
10
0
0
20
10
10
% I
% Lys:
0
10
0
10
0
0
0
0
0
0
10
10
0
0
10
% K
% Leu:
0
0
10
20
20
10
20
10
0
10
0
20
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
10
30
0
10
10
10
0
0
0
% N
% Pro:
40
10
10
20
10
30
10
10
30
0
0
20
0
20
0
% P
% Gln:
20
10
20
0
20
10
0
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
20
0
10
0
20
10
0
0
30
% R
% Ser:
20
0
10
10
20
0
20
0
10
0
0
0
0
0
0
% S
% Thr:
10
10
0
0
0
0
0
20
0
0
20
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
10
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _