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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLP1 All Species: 20.91
Human Site: S369 Identified Species: 41.82
UniProt: Q92989 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92989 NP_001136069.1 425 47646 S369 V H H L L S V S T A E G T E E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q99LI9 425 47719 S369 V H H L L S V S T A E G T E E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJL4 425 47557 S369 V H H L L S V S M A D S P D D
Frog Xenopus laevis Q6NS21 439 48318 V381 A H H L L S V V P L D G G S A
Zebra Danio Brachydanio rerio XP_693984 443 48556 S382 T H H V L S V S S V D D E A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K284 423 46772 S365 I H H V L A L S F A E S V E D
Honey Bee Apis mellifera XP_623706 422 46700 S366 L H H L L S V S F A D S P E D
Nematode Worm Caenorhab. elegans P52874 428 47580 S370 K H H L F A F S R S T K A D E
Sea Urchin Strong. purpuratus XP_001199603 359 40079 A318 D L L S T N V A G F I V I T N
Poplar Tree Populus trichocarpa XP_002323828 437 47948 V382 L L H V V L A V S Y A Q E P D
Maize Zea mays NP_001151165 439 47649 I384 M I H T V L A I S Y A K E P E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SAB7 491 53418 A432 W T L A V M I A S V T D S P Q
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 98.5 N.A. N.A. N.A. 93.1 75.6 76.3 N.A. 55.5 60.7 48.1 52.2
Protein Similarity: 100 N.A. N.A. N.A. N.A. 99.2 N.A. N.A. N.A. 97.4 85.1 86.6 N.A. 73.6 79 66.3 68.9
P-Site Identity: 100 N.A. N.A. N.A. N.A. 100 N.A. N.A. N.A. 60 46.6 46.6 N.A. 46.6 60 33.3 6.6
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 100 N.A. N.A. N.A. 80 53.3 66.6 N.A. 80 80 53.3 20
Percent
Protein Identity: 42.1 40.5 N.A. N.A. N.A. 27
Protein Similarity: 60.6 59.9 N.A. N.A. N.A. 46.4
P-Site Identity: 6.6 13.3 N.A. N.A. N.A. 0
P-Site Similarity: 40 33.3 N.A. N.A. N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 9 0 17 17 17 0 42 17 0 9 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 34 17 0 17 34 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 25 0 25 34 42 % E
% Phe: 0 0 0 0 9 0 9 0 17 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 9 0 0 25 9 0 0 % G
% His: 0 67 84 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 0 0 0 0 9 9 0 0 9 0 9 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % K
% Leu: 17 17 17 50 59 17 9 0 0 9 0 0 0 0 0 % L
% Met: 9 0 0 0 0 9 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 9 0 0 0 17 25 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % Q
% Arg: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % R
% Ser: 0 0 0 9 0 50 0 59 34 9 0 25 9 9 0 % S
% Thr: 9 9 0 9 9 0 0 0 17 0 17 0 17 9 0 % T
% Val: 25 0 0 25 25 0 59 17 0 17 0 9 9 0 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _