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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CLP1 All Species: 19.09
Human Site: Y263 Identified Species: 38.18
UniProt: Q92989 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92989 NP_001136069.1 425 47646 Y263 V L D Q E R L Y N E L K R D L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q99LI9 425 47719 Y263 V L D Q E R L Y N E L K R D L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZJL4 425 47557 Y263 V L D Q E R L Y N E L K R D L
Frog Xenopus laevis Q6NS21 439 48318 Y275 V L D Q E R L Y N D L L R D L
Zebra Danio Brachydanio rerio XP_693984 443 48556 N276 L D Q E R L Y N E L K R D L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K284 423 46772 N259 L D Q E R L Y N E L L R D V P
Honey Bee Apis mellifera XP_623706 422 46700 Y260 V L D Q E R L Y N E L V R D M
Nematode Worm Caenorhab. elegans P52874 428 47580 S264 L D H E R L Y S D L S K E L P
Sea Urchin Strong. purpuratus XP_001199603 359 40079 T212 Q S G C V I N T C G W I K G E
Poplar Tree Populus trichocarpa XP_002323828 437 47948 M276 G Q E K L F S M L R D V L K S
Maize Zea mays NP_001151165 439 47649 M278 G Q E K L W K M L K D A V Q S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SAB7 491 53418 Q326 V V V L G S E Q L K T E L G Q
Conservation
Percent
Protein Identity: 100 N.A. N.A. N.A. N.A. 98.5 N.A. N.A. N.A. 93.1 75.6 76.3 N.A. 55.5 60.7 48.1 52.2
Protein Similarity: 100 N.A. N.A. N.A. N.A. 99.2 N.A. N.A. N.A. 97.4 85.1 86.6 N.A. 73.6 79 66.3 68.9
P-Site Identity: 100 N.A. N.A. N.A. N.A. 100 N.A. N.A. N.A. 100 86.6 0 N.A. 6.6 86.6 6.6 0
P-Site Similarity: 100 N.A. N.A. N.A. N.A. 100 N.A. N.A. N.A. 100 93.3 20 N.A. 26.6 93.3 26.6 6.6
Percent
Protein Identity: 42.1 40.5 N.A. N.A. N.A. 27
Protein Similarity: 60.6 59.9 N.A. N.A. N.A. 46.4
P-Site Identity: 0 0 N.A. N.A. N.A. 6.6
P-Site Similarity: 13.3 20 N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 25 42 0 0 0 0 0 9 9 17 0 17 42 0 % D
% Glu: 0 0 17 25 42 0 9 0 17 34 0 9 9 0 9 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 9 0 9 0 0 0 0 9 0 0 0 17 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 17 0 0 9 0 0 17 9 34 9 9 0 % K
% Leu: 25 42 0 9 17 25 42 0 25 25 50 9 17 17 34 % L
% Met: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 9 % M
% Asn: 0 0 0 0 0 0 9 17 42 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % P
% Gln: 9 17 17 42 0 0 0 9 0 0 0 0 0 9 9 % Q
% Arg: 0 0 0 0 25 42 0 0 0 9 0 17 42 0 0 % R
% Ser: 0 9 0 0 0 9 9 9 0 0 9 0 0 0 17 % S
% Thr: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % T
% Val: 50 9 9 0 9 0 0 0 0 0 0 17 9 9 0 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 25 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _