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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KAT5 All Species: 23.64
Human Site: S208 Identified Species: 37.14
UniProt: Q92993 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92993 NP_006379.2 513 58582 S208 D S S D G I P S A P R M T G S
Chimpanzee Pan troglodytes XP_508558 546 61795 S241 D S S D G I P S A P R M T G S
Rhesus Macaque Macaca mulatta XP_001113038 442 50153 T147 L Q P N H R S T K R K V E V V
Dog Lupus familis XP_540849 546 61797 S241 D S S D G I P S A P R M T G S
Cat Felis silvestris
Mouse Mus musculus Q8CHK4 513 58580 S208 D S S D G I P S A P R M T G S
Rat Rattus norvegicus Q5XI06 458 52614 T163 Y A E M D P T T A A L E K E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q92021 609 68857 A280 A I V A P L E A S L K V T E Q
Zebra Danio Brachydanio rerio NP_001013327 538 61712 S233 D S S D G I P S A P R M T G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 P238 G S Q D G K T P T P R Q S G S
Honey Bee Apis mellifera XP_396552 453 52544 A158 R P T G S L V A H H H D D I V
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 S163 S M S M V G H S E D A M T R I
Sea Urchin Strong. purpuratus XP_786024 440 50807 A144 R Q T G S M V A D K N H D D I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 H150 K R K I D E T H I E G H E E L
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 T150 D E I K K L R T S G S M T Q N
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 Q194 P A A K K Q R Q P S F S R E Q
Conservation
Percent
Protein Identity: 100 93.9 86.1 93.7 N.A. 99.8 37.2 N.A. N.A. N.A. 20.2 76.9 N.A. 56.5 59.2 44.4 60
Protein Similarity: 100 93.9 86.1 93.9 N.A. 100 53.2 N.A. N.A. N.A. 34.9 82.3 N.A. 67.2 71.5 59.8 70.1
P-Site Identity: 100 100 0 100 N.A. 100 6.6 N.A. N.A. N.A. 6.6 100 N.A. 46.6 0 26.6 0
P-Site Similarity: 100 100 26.6 100 N.A. 100 20 N.A. N.A. N.A. 40 100 N.A. 53.3 20 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. 38.9 39.3 41.9
Protein Similarity: N.A. N.A. N.A. 54.5 55.9 58
P-Site Identity: N.A. N.A. N.A. 0 20 0
P-Site Similarity: N.A. N.A. N.A. 0 46.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 7 7 0 0 0 20 40 7 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 40 0 0 40 14 0 0 0 7 7 0 7 14 7 0 % D
% Glu: 0 7 7 0 0 7 7 0 7 7 0 7 14 27 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 7 0 0 14 40 7 0 0 0 7 7 0 0 40 0 % G
% His: 0 0 0 0 7 0 7 7 7 7 7 14 0 0 7 % H
% Ile: 0 7 7 7 0 34 0 0 7 0 0 0 0 7 14 % I
% Lys: 7 0 7 14 14 7 0 0 7 7 14 0 7 0 0 % K
% Leu: 7 0 0 0 0 20 0 0 0 7 7 0 0 0 7 % L
% Met: 0 7 0 14 0 7 0 0 0 0 0 47 0 0 0 % M
% Asn: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 7 % N
% Pro: 7 7 7 0 7 7 34 7 7 40 0 0 0 0 0 % P
% Gln: 0 14 7 0 0 7 0 7 0 0 0 7 0 7 14 % Q
% Arg: 14 7 0 0 0 7 14 0 0 7 40 0 7 7 0 % R
% Ser: 7 40 40 0 14 0 7 40 14 7 7 7 7 0 40 % S
% Thr: 0 0 14 0 0 0 20 20 7 0 0 0 54 0 0 % T
% Val: 0 0 7 0 7 0 14 0 0 0 0 14 0 7 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _