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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KAT5 All Species: 21.82
Human Site: S457 Identified Species: 34.29
UniProt: Q92993 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92993 NP_006379.2 513 58582 S457 I K K E D V I S T L Q Y L N L
Chimpanzee Pan troglodytes XP_508558 546 61795 S490 I K K E D V I S T L Q Y L N L
Rhesus Macaque Macaca mulatta XP_001113038 442 50153 L392 L I E F S Y E L S K V E G K T
Dog Lupus familis XP_540849 546 61797 S490 I K K E D V I S T L Q Y L N L
Cat Felis silvestris
Mouse Mus musculus Q8CHK4 513 58580 S457 I K K E D V I S T L Q Y L N L
Rat Rattus norvegicus Q5XI06 458 52614 Y408 Q S L N M V K Y W K G Q H V I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q92021 609 68857 S538 N A Y K A L E S P S K S L S L
Zebra Danio Brachydanio rerio NP_001013327 538 61712 S482 V K K E D V I S T L Q Y L N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 I485 S I K K E D V I S T L Q N L N
Honey Bee Apis mellifera XP_396552 453 52544 N403 I S T L Q N L N L I N Y Y K G
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 Y408 Q L D L Y K Y Y K G S Y I I V
Sea Urchin Strong. purpuratus XP_786024 440 50807 L389 V I Y T L C N L N L I N Y Y K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 L395 A E D I L S T L Q S L E L I Q
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 R395 A K T L N I L R Y Y K G Q H I
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 Q450 Q D V E H T L Q A L K M Q V Y
Conservation
Percent
Protein Identity: 100 93.9 86.1 93.7 N.A. 99.8 37.2 N.A. N.A. N.A. 20.2 76.9 N.A. 56.5 59.2 44.4 60
Protein Similarity: 100 93.9 86.1 93.9 N.A. 100 53.2 N.A. N.A. N.A. 34.9 82.3 N.A. 67.2 71.5 59.8 70.1
P-Site Identity: 100 100 0 100 N.A. 100 6.6 N.A. N.A. N.A. 20 93.3 N.A. 6.6 13.3 6.6 6.6
P-Site Similarity: 100 100 20 100 N.A. 100 13.3 N.A. N.A. N.A. 46.6 100 N.A. 33.3 33.3 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. 38.9 39.3 41.9
Protein Similarity: N.A. N.A. N.A. 54.5 55.9 58
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. 13.3 46.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 0 0 7 0 0 0 7 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 14 0 34 7 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 7 7 40 7 0 14 0 0 0 0 14 0 0 0 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 7 7 7 7 0 7 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 7 7 0 % H
% Ile: 34 20 0 7 0 7 34 7 0 7 7 0 7 14 14 % I
% Lys: 0 40 40 14 0 7 7 0 7 14 20 0 0 14 7 % K
% Leu: 7 7 7 20 14 7 20 20 7 47 14 0 47 7 40 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 7 0 0 7 7 7 7 7 7 0 7 7 7 34 7 % N
% Pro: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % P
% Gln: 20 0 0 0 7 0 0 7 7 0 34 14 14 0 7 % Q
% Arg: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % R
% Ser: 7 14 0 0 7 7 0 40 14 14 7 7 0 7 0 % S
% Thr: 0 0 14 7 0 7 7 0 34 7 0 0 0 0 7 % T
% Val: 14 0 7 0 0 40 7 0 0 0 7 0 0 14 7 % V
% Trp: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % W
% Tyr: 0 0 14 0 7 7 7 14 7 7 0 47 14 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _