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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KAT5 All Species: 24.24
Human Site: S497 Identified Species: 38.1
UniProt: Q92993 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92993 NP_006379.2 513 58582 S497 K R L L R I D S K C L H F T P
Chimpanzee Pan troglodytes XP_508558 546 61795 S530 K R L L R I D S K C L H F T P
Rhesus Macaque Macaca mulatta XP_001113038 442 50153 M427 Q T I L E I L M G L K S E S G
Dog Lupus familis XP_540849 546 61797 S530 K R L L R I D S K C L H F T P
Cat Felis silvestris
Mouse Mus musculus Q8CHK4 513 58580 S497 K R L L R I D S K C L H F T P
Rat Rattus norvegicus Q5XI06 458 52614 L443 I T V D S V C L K W A P P K H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q92021 609 68857 S590 E K L Y P Y L S P F L H D S G
Zebra Danio Brachydanio rerio NP_001013327 538 61712 S522 K R H L R I D S K C L H F T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 S526 K R K I R I D S K C L H W T P
Honey Bee Apis mellifera XP_396552 453 52544 K438 R Q I R I D P K C L H W T P K
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 Q443 R I N P A A L Q W R P K E Y G
Sea Urchin Strong. purpuratus XP_786024 440 50807 P424 K R K I R I D P K S L H W T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 D430 A A G R G G L D V D A S K L I
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 I430 T I D P N R L I W K P P V F T
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 P487 K Q K R L I D P E R I Q W K P
Conservation
Percent
Protein Identity: 100 93.9 86.1 93.7 N.A. 99.8 37.2 N.A. N.A. N.A. 20.2 76.9 N.A. 56.5 59.2 44.4 60
Protein Similarity: 100 93.9 86.1 93.9 N.A. 100 53.2 N.A. N.A. N.A. 34.9 82.3 N.A. 67.2 71.5 59.8 70.1
P-Site Identity: 100 100 13.3 100 N.A. 100 6.6 N.A. N.A. N.A. 26.6 93.3 N.A. 80 0 0 66.6
P-Site Similarity: 100 100 33.3 100 N.A. 100 20 N.A. N.A. N.A. 46.6 93.3 N.A. 93.3 20 6.6 80
Percent
Protein Identity: N.A. N.A. N.A. 38.9 39.3 41.9
Protein Similarity: N.A. N.A. N.A. 54.5 55.9 58
P-Site Identity: N.A. N.A. N.A. 0 0 26.6
P-Site Similarity: N.A. N.A. N.A. 0 0 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 7 7 0 0 0 0 14 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 7 40 0 0 0 0 0 % C
% Asp: 0 0 7 7 0 7 54 7 0 7 0 0 7 0 0 % D
% Glu: 7 0 0 0 7 0 0 0 7 0 0 0 14 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 34 7 0 % F
% Gly: 0 0 7 0 7 7 0 0 7 0 0 0 0 0 20 % G
% His: 0 0 7 0 0 0 0 0 0 0 7 54 0 0 7 % H
% Ile: 7 14 14 14 7 60 0 7 0 0 7 0 0 0 7 % I
% Lys: 54 7 20 0 0 0 0 7 54 7 7 7 7 14 7 % K
% Leu: 0 0 34 40 7 0 34 7 0 14 54 0 0 7 0 % L
% Met: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 14 7 0 7 14 7 0 14 14 7 7 54 % P
% Gln: 7 14 0 0 0 0 0 7 0 0 0 7 0 0 0 % Q
% Arg: 14 47 0 20 47 7 0 0 0 14 0 0 0 0 0 % R
% Ser: 0 0 0 0 7 0 0 47 0 7 0 14 0 14 0 % S
% Thr: 7 14 0 0 0 0 0 0 0 0 0 0 7 47 7 % T
% Val: 0 0 7 0 0 7 0 0 7 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 14 7 0 7 20 0 0 % W
% Tyr: 0 0 0 7 0 7 0 0 0 0 0 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _