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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KAT5 All Species: 27.58
Human Site: Y250 Identified Species: 43.33
UniProt: Q92993 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92993 NP_006379.2 513 58582 Y250 K P W Y F S P Y P Q E L T T L
Chimpanzee Pan troglodytes XP_508558 546 61795 Y283 K P W Y F S P Y P Q E L T T L
Rhesus Macaque Macaca mulatta XP_001113038 442 50153 G185 R A V A A Q P G R K R K S N C
Dog Lupus familis XP_540849 546 61797 Y283 K P W Y F S P Y P Q E L T T L
Cat Felis silvestris
Mouse Mus musculus Q8CHK4 513 58580 Y250 K P W Y F S P Y P Q E L T T L
Rat Rattus norvegicus Q5XI06 458 52614 Y201 F S P F P E D Y G K Q P K L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q92021 609 68857 Q331 R E E K L L E Q L K E Q G E N
Zebra Danio Brachydanio rerio NP_001013327 538 61712 Y275 K P W Y F S P Y P Q E L T T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 Y278 K P W Y F S P Y P Q E L C Q M
Honey Bee Apis mellifera XP_396552 453 52544 L196 Y P Q E M V H L P C I Y I C E
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 I201 Q L T S L D C I Y I C E F C L
Sea Urchin Strong. purpuratus XP_786024 440 50807 S182 P Y P I E L T S K P K I Y L C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 Y188 K Y E I E T W Y F S P F P P E
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 E188 Y F S P Y P I E L T D E D F I
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 Y243 F P W Y F S P Y P Q I F D Q E
Conservation
Percent
Protein Identity: 100 93.9 86.1 93.7 N.A. 99.8 37.2 N.A. N.A. N.A. 20.2 76.9 N.A. 56.5 59.2 44.4 60
Protein Similarity: 100 93.9 86.1 93.9 N.A. 100 53.2 N.A. N.A. N.A. 34.9 82.3 N.A. 67.2 71.5 59.8 70.1
P-Site Identity: 100 100 6.6 100 N.A. 100 6.6 N.A. N.A. N.A. 6.6 100 N.A. 80 13.3 6.6 0
P-Site Similarity: 100 100 26.6 100 N.A. 100 26.6 N.A. N.A. N.A. 20 100 N.A. 86.6 13.3 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 38.9 39.3 41.9
Protein Similarity: N.A. N.A. N.A. 54.5 55.9 58
P-Site Identity: N.A. N.A. N.A. 13.3 0 60
P-Site Similarity: N.A. N.A. N.A. 20 20 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 7 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 7 7 0 7 14 14 % C
% Asp: 0 0 0 0 0 7 7 0 0 0 7 0 14 0 0 % D
% Glu: 0 7 14 7 14 7 7 7 0 0 47 14 0 7 20 % E
% Phe: 14 7 0 7 47 0 0 0 7 0 0 14 7 7 0 % F
% Gly: 0 0 0 0 0 0 0 7 7 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 14 0 0 7 7 0 7 14 7 7 0 7 % I
% Lys: 47 0 0 7 0 0 0 0 7 20 7 7 7 0 0 % K
% Leu: 0 7 0 0 14 14 0 7 14 0 0 40 0 14 40 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % N
% Pro: 7 54 14 7 7 7 54 0 54 7 7 7 7 7 0 % P
% Gln: 7 0 7 0 0 7 0 7 0 47 7 7 0 14 0 % Q
% Arg: 14 0 0 0 0 0 0 0 7 0 7 0 0 0 0 % R
% Ser: 0 7 7 7 0 47 0 7 0 7 0 0 7 0 0 % S
% Thr: 0 0 7 0 0 7 7 0 0 7 0 0 34 34 0 % T
% Val: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 47 0 0 0 7 0 0 0 0 0 0 0 7 % W
% Tyr: 14 14 0 47 7 0 0 60 7 0 0 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _