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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 37.58
Human Site: S226 Identified Species: 63.59
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S226 M H T G R R P S G L C G A A L
Chimpanzee Pan troglodytes XP_510208 819 88957 S368 M H T G R R P S G L C G A A L
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 L168 Y V L G K T F L L L A R E L C
Dog Lupus familis XP_548005 637 70371 V206 M H D F R R T V K E V I S V V
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 S226 M H T G R R P S G L C G A A L
Rat Rattus norvegicus NP_001100231 686 74096 S236 M H T G R R P S G L C G A A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 S227 M H T G R R P S G L C G A A L
Frog Xenopus laevis NP_001088063 660 73751 R223 R D W M H T G R R P S G L C G
Zebra Danio Brachydanio rerio NP_956183 693 76806 S225 M H T G R R P S G L C G A A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 T227 M H S G R R P T G L C G A A L
Honey Bee Apis mellifera XP_623775 648 73504 S217 V Q R M K R D S I H S G R R P
Nematode Worm Caenorhab. elegans NP_495526 759 84015 T221 M S T G R R P T G I C G A A L
Sea Urchin Strong. purpuratus XP_794011 768 83924 S228 M H T G R R P S G L C G A A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 V165 G A T F L K M V K K L H I T E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 13.3 26.6 N.A. 100 100 N.A. N.A. 100 6.6 100 N.A. 86.6 20 80 100
P-Site Similarity: 100 100 20 40 N.A. 100 100 N.A. N.A. 100 6.6 100 N.A. 100 33.3 93.3 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 8 0 65 65 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 65 0 0 8 8 % C
% Asp: 0 8 8 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 8 % E
% Phe: 0 0 0 15 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 72 0 0 8 0 65 0 0 79 0 0 8 % G
% His: 0 65 0 0 8 0 0 0 0 8 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 8 0 8 8 0 0 % I
% Lys: 0 0 0 0 15 8 0 0 15 8 0 0 0 0 0 % K
% Leu: 0 0 8 0 8 0 0 8 8 65 8 0 8 8 65 % L
% Met: 72 0 0 15 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 65 0 0 8 0 0 0 0 8 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 0 8 0 72 79 0 8 8 0 0 8 8 8 0 % R
% Ser: 0 8 8 0 0 0 0 58 0 0 15 0 8 0 0 % S
% Thr: 0 0 65 0 0 15 8 15 0 0 0 0 0 8 0 % T
% Val: 8 8 0 0 0 0 0 15 0 0 8 0 0 8 8 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _