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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRF1
All Species:
26.36
Human Site:
S258
Identified Species:
44.62
UniProt:
Q92994
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92994
NP_001510.2
677
73840
S258
S
V
V
K
V
C
E
S
T
L
R
K
R
L
T
Chimpanzee
Pan troglodytes
XP_510208
819
88957
S400
S
V
V
K
V
C
E
S
T
L
R
K
R
L
T
Rhesus Macaque
Macaca mulatta
XP_001098066
599
65136
F196
R
F
A
H
L
L
E
F
G
E
K
N
H
E
V
Dog
Lupus familis
XP_548005
637
70371
Q234
F
E
D
T
P
T
S
Q
L
T
V
D
E
F
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFK2
676
73781
S258
S
V
V
K
V
C
E
S
T
L
R
K
R
L
T
Rat
Rattus norvegicus
NP_001100231
686
74096
S268
S
V
V
K
V
C
E
S
T
L
R
K
R
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421405
681
75256
S259
R
V
V
K
V
C
E
S
T
L
R
K
R
L
T
Frog
Xenopus laevis
NP_001088063
660
73751
V252
T
I
K
E
V
I
R
V
V
K
V
C
E
S
T
Zebra Danio
Brachydanio rerio
NP_956183
693
76806
T257
S
V
V
K
V
C
E
T
T
L
R
K
R
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650616
662
73627
S259
G
V
V
K
I
H
E
S
T
L
R
K
R
L
S
Honey Bee
Apis mellifera
XP_623775
648
73504
P245
L
H
E
F
N
R
S
P
T
D
I
I
K
I
V
Nematode Worm
Caenorhab. elegans
NP_495526
759
84015
G253
R
V
V
H
I
S
E
G
V
I
R
K
R
L
D
Sea Urchin
Strong. purpuratus
XP_794011
768
83924
A260
K
V
V
K
V
C
D
A
T
L
R
K
R
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29056
596
66888
D193
A
E
K
L
D
L
A
D
K
K
I
K
V
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
86.4
82.7
N.A.
89.8
81.6
N.A.
N.A.
78.1
72.5
65.9
N.A.
42.5
43.4
32.4
46.3
Protein Similarity:
100
80
87
85.9
N.A.
93.3
86
N.A.
N.A.
87
84.7
77.6
N.A.
59.6
61.7
50
60.1
P-Site Identity:
100
100
6.6
0
N.A.
100
100
N.A.
N.A.
93.3
13.3
93.3
N.A.
73.3
6.6
46.6
73.3
P-Site Similarity:
100
100
20
0
N.A.
100
100
N.A.
N.A.
93.3
33.3
100
N.A.
86.6
20
60
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
50
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
8
0
8
0
8
8
0
8
0
8
0
0
8
% D
% Glu:
0
15
8
8
0
0
65
0
0
8
0
0
15
8
0
% E
% Phe:
8
8
0
8
0
0
0
8
0
0
0
0
0
8
0
% F
% Gly:
8
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% G
% His:
0
8
0
15
0
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
15
8
0
0
0
8
15
8
0
8
0
% I
% Lys:
8
0
15
58
0
0
0
0
8
15
8
72
8
0
8
% K
% Leu:
8
0
0
8
8
15
0
0
8
58
0
0
0
65
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
22
0
0
0
0
8
8
0
0
0
65
0
65
0
0
% R
% Ser:
36
0
0
0
0
8
15
43
0
0
0
0
0
8
15
% S
% Thr:
8
0
0
8
0
8
0
8
65
8
0
0
0
0
50
% T
% Val:
0
65
65
0
58
0
0
8
15
0
15
0
8
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _