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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 26.06
Human Site: S293 Identified Species: 44.1
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S293 E E E C D P P S Y T A G Q R K
Chimpanzee Pan troglodytes XP_510208 819 88957 S435 E E E C D P P S Y T A G Q R K
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 C229 G R R P S G L C G A A L L V A
Dog Lupus familis XP_548005 637 70371 E267 K L R L K Q L E Q V L S K K L
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 S293 E E E C D P P S Y T A G Q R K
Rat Rattus norvegicus NP_001100231 686 74096 S303 E E E C D P P S Y T A G Q R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 S294 E E E C D P P S F T A G Q K K
Frog Xenopus laevis NP_001088063 660 73751 L285 D E F M K V D L E Q E C D P P
Zebra Danio Brachydanio rerio NP_956183 693 76806 S292 E K E C D P P S F V A G Q K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 P292 D L E R E Q D P P S F K A A R
Honey Bee Apis mellifera XP_623775 648 73504 E278 S S A L T L E E F M T V D L E
Nematode Worm Caenorhab. elegans NP_495526 759 84015 A288 E H S E D P P A Y R E S R R K
Sea Urchin Strong. purpuratus XP_794011 768 83924 S295 E E E Q D P P S F T R G R R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 A226 R P A G I A G A C I L L A C R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 6.6 0 N.A. 100 100 N.A. N.A. 86.6 6.6 73.3 N.A. 6.6 0 46.6 66.6
P-Site Similarity: 100 100 6.6 20 N.A. 100 100 N.A. N.A. 100 13.3 93.3 N.A. 33.3 13.3 60 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 15 0 0 8 0 15 0 8 50 0 15 8 8 % A
% Cys: 0 0 0 43 0 0 0 8 8 0 0 8 0 8 0 % C
% Asp: 15 0 0 0 58 0 15 0 0 0 0 0 15 0 0 % D
% Glu: 58 50 58 8 8 0 8 15 8 0 15 0 0 0 8 % E
% Phe: 0 0 8 0 0 0 0 0 29 0 8 0 0 0 0 % F
% Gly: 8 0 0 8 0 8 8 0 8 0 0 50 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 8 8 0 0 15 0 0 0 0 0 0 8 8 22 50 % K
% Leu: 0 15 0 15 0 8 15 8 0 0 15 15 8 8 8 % L
% Met: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 8 0 58 58 8 8 0 0 0 0 8 8 % P
% Gln: 0 0 0 8 0 15 0 0 8 8 0 0 43 0 0 % Q
% Arg: 8 8 15 8 0 0 0 0 0 8 8 0 15 43 15 % R
% Ser: 8 8 8 0 8 0 0 50 0 8 0 15 0 0 0 % S
% Thr: 0 0 0 0 8 0 0 0 0 43 8 0 0 0 8 % T
% Val: 0 0 0 0 0 8 0 0 0 15 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 36 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _