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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 7.58
Human Site: S322 Identified Species: 12.82
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S322 E E V E G E I S S Y Q D A I E
Chimpanzee Pan troglodytes XP_510208 819 88957 S464 E E V E G E I S S Y Q D A I E
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 E257 I S V V K V C E S T L R K R W
Dog Lupus familis XP_548005 637 70371 S295 I E I E L E N S R P K A K G A
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 I321 L E E V E G E I S S Y Q D A I
Rat Rattus norvegicus NP_001100231 686 74096 I331 L E E V E G E I S T Y Q D A I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 D327 G E I S S Y Q D E I E I E L E
Frog Xenopus laevis NP_001088063 660 73751 L314 E Q E L S K K L D E V E G E I
Zebra Danio Brachydanio rerio NP_956183 693 76806 D321 E E Y Q G E I D S Y R D E I E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 E320 E L T E L Q K E I D A H L E K
Honey Bee Apis mellifera XP_623775 648 73504 R306 K D R E R L Q R L E N I D T E
Nematode Worm Caenorhab. elegans NP_495526 759 84015 A320 E Q L G E M E A H V E A A L D
Sea Urchin Strong. purpuratus XP_794011 768 83924 H389 I E N K V N S H K Q S Q G V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 T254 V S H V A E E T L Q Q R L N E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 13.3 26.6 N.A. 13.3 13.3 N.A. N.A. 13.3 6.6 66.6 N.A. 13.3 13.3 13.3 6.6
P-Site Similarity: 100 100 13.3 40 N.A. 13.3 13.3 N.A. N.A. 33.3 26.6 80 N.A. 26.6 26.6 53.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 8 0 0 8 15 22 15 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 15 8 8 0 22 22 0 15 % D
% Glu: 43 58 22 36 22 36 29 15 8 15 15 8 15 15 43 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 22 15 0 0 0 0 0 0 15 8 0 % G
% His: 0 0 8 0 0 0 0 8 8 0 0 8 0 0 0 % H
% Ile: 22 0 15 0 0 0 22 15 8 8 0 15 0 22 22 % I
% Lys: 8 0 0 8 8 8 15 0 8 0 8 0 15 0 8 % K
% Leu: 15 8 8 8 15 8 0 8 15 0 8 0 15 15 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 8 8 0 0 0 8 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % P
% Gln: 0 15 0 8 0 8 15 0 0 15 22 22 0 0 0 % Q
% Arg: 0 0 8 0 8 0 0 8 8 0 8 15 0 8 0 % R
% Ser: 0 15 0 8 15 0 8 22 43 8 8 0 0 0 0 % S
% Thr: 0 0 8 0 0 0 0 8 0 15 0 0 0 8 0 % T
% Val: 8 0 22 29 8 8 0 0 0 8 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 8 0 0 8 0 0 0 22 15 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _