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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 9.7
Human Site: S357 Identified Species: 16.41
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S357 G S T E D T A S S L C G E E D
Chimpanzee Pan troglodytes XP_510208 819 88957 S499 G S T E D T A S S L C G E E D
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 L292 E D T E D E E L E A A A S H L
Dog Lupus familis XP_548005 637 70371 L330 E D P E D E E L E A V A S H L
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 T356 D G S G E D A T S S P R C E E
Rat Rattus norvegicus NP_001100231 686 74096 T366 D G S G E D A T S S P F C E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 G362 D N T L S I F G E E E A E D E
Frog Xenopus laevis NP_001088063 660 73751 D349 M Y A S Y S K D D A E D N T S
Zebra Danio Brachydanio rerio NP_956183 693 76806 V356 E D D D S L S V T S G L T G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 P355 P L S S P S T P N S S S E K D
Honey Bee Apis mellifera XP_623775 648 73504 I341 R K R K D A A I I E K E D T D
Nematode Worm Caenorhab. elegans NP_495526 759 84015 Q355 G K E N D K M Q T L T E T V V
Sea Urchin Strong. purpuratus XP_794011 768 83924 E424 G G D G R E G E E K G G G D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 S289 D G E A R P P S F V K N R K K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 20 13.3 N.A. 20 20 N.A. N.A. 13.3 0 6.6 N.A. 13.3 20 20 13.3
P-Site Similarity: 100 100 20 13.3 N.A. 46.6 46.6 N.A. N.A. 33.3 6.6 26.6 N.A. 40 33.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 36 0 0 22 8 22 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 15 0 15 0 0 % C
% Asp: 29 22 15 8 43 15 0 8 8 0 0 8 8 15 36 % D
% Glu: 22 0 15 29 15 22 15 8 29 15 15 15 29 29 22 % E
% Phe: 0 0 0 0 0 0 8 0 8 0 0 8 0 0 0 % F
% Gly: 29 29 0 22 0 0 8 8 0 0 15 22 8 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % H
% Ile: 0 0 0 0 0 8 0 8 8 0 0 0 0 0 0 % I
% Lys: 0 15 0 8 0 8 8 0 0 8 15 0 0 15 8 % K
% Leu: 0 8 0 8 0 8 0 15 0 22 0 8 0 0 15 % L
% Met: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 0 0 8 0 0 8 8 0 0 % N
% Pro: 8 0 8 0 8 8 8 8 0 0 15 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 8 0 8 0 15 0 0 0 0 0 0 8 8 0 0 % R
% Ser: 0 15 22 15 15 15 8 22 29 29 8 8 15 0 8 % S
% Thr: 0 0 29 0 0 15 8 15 15 0 8 0 15 15 0 % T
% Val: 0 0 0 0 0 0 0 8 0 8 8 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _