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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRF1
All Species:
16.97
Human Site:
S433
Identified Species:
28.72
UniProt:
Q92994
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92994
NP_001510.2
677
73840
S433
S
I
R
E
C
I
S
S
Q
S
S
D
P
K
D
Chimpanzee
Pan troglodytes
XP_510208
819
88957
S575
S
I
R
E
C
I
S
S
Q
S
S
D
P
K
D
Rhesus Macaque
Macaca mulatta
XP_001098066
599
65136
E368
K
D
A
S
G
D
G
E
L
D
L
S
G
I
D
Dog
Lupus familis
XP_548005
637
70371
G406
P
T
D
P
C
G
D
G
E
L
D
L
S
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFK2
676
73781
S432
S
I
R
E
C
I
S
S
P
S
G
D
P
K
D
Rat
Rattus norvegicus
NP_001100231
686
74096
S442
S
I
R
E
C
I
S
S
P
S
G
D
P
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421405
681
75256
S438
S
I
K
E
C
I
S
S
K
D
R
E
P
G
E
Frog
Xenopus laevis
NP_001088063
660
73751
M425
S
I
K
E
C
I
A
M
H
E
Q
E
K
S
D
Zebra Danio
Brachydanio rerio
NP_956183
693
76806
T432
S
A
A
S
L
G
L
T
D
S
I
R
Q
C
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650616
662
73627
E431
E
K
A
K
Q
P
Q
E
Q
E
L
I
T
D
D
Honey Bee
Apis mellifera
XP_623775
648
73504
F417
K
E
S
V
N
I
N
F
E
N
N
S
G
E
I
Nematode Worm
Caenorhab. elegans
NP_495526
759
84015
D431
P
H
P
I
V
N
A
D
L
E
E
D
I
S
D
Sea Urchin
Strong. purpuratus
XP_794011
768
83924
A500
E
S
I
I
K
E
A
A
I
P
E
E
K
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29056
596
66888
N365
T
N
G
I
D
G
E
N
I
Y
H
E
G
S
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
86.4
82.7
N.A.
89.8
81.6
N.A.
N.A.
78.1
72.5
65.9
N.A.
42.5
43.4
32.4
46.3
Protein Similarity:
100
80
87
85.9
N.A.
93.3
86
N.A.
N.A.
87
84.7
77.6
N.A.
59.6
61.7
50
60.1
P-Site Identity:
100
100
6.6
6.6
N.A.
86.6
86.6
N.A.
N.A.
53.3
40
13.3
N.A.
13.3
6.6
13.3
0
P-Site Similarity:
100
100
6.6
13.3
N.A.
86.6
86.6
N.A.
N.A.
80
60
20
N.A.
20
40
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
22
0
0
0
22
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
50
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
8
0
8
8
8
8
8
15
8
36
0
8
58
% D
% Glu:
15
8
0
43
0
8
8
15
15
22
15
29
0
8
15
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
22
8
8
0
0
15
0
22
15
0
% G
% His:
0
8
0
0
0
0
0
0
8
0
8
0
0
0
0
% H
% Ile:
0
43
8
22
0
50
0
0
15
0
8
8
8
8
22
% I
% Lys:
15
8
15
8
8
0
0
0
8
0
0
0
15
29
0
% K
% Leu:
0
0
0
0
8
0
8
0
15
8
15
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
8
8
8
0
8
8
0
0
0
0
% N
% Pro:
15
0
8
8
0
8
0
0
15
8
0
0
36
0
8
% P
% Gln:
0
0
0
0
8
0
8
0
22
0
8
0
8
0
0
% Q
% Arg:
0
0
29
0
0
0
0
0
0
0
8
8
0
0
0
% R
% Ser:
50
8
8
15
0
0
36
36
0
36
15
15
8
29
0
% S
% Thr:
8
8
0
0
0
0
0
8
0
0
0
0
8
0
0
% T
% Val:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _