KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRF1
All Species:
23.64
Human Site:
S450
Identified Species:
40
UniProt:
Q92994
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92994
NP_001510.2
677
73840
S450
G
D
G
E
L
D
L
S
G
I
D
D
L
E
I
Chimpanzee
Pan troglodytes
XP_510208
819
88957
S592
G
D
G
E
L
D
L
S
G
I
D
D
L
E
I
Rhesus Macaque
Macaca mulatta
XP_001098066
599
65136
N385
E
I
D
R
Y
I
L
N
E
S
E
A
R
V
K
Dog
Lupus familis
XP_548005
637
70371
L423
L
E
I
D
R
Y
I
L
N
E
A
E
A
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFK2
676
73781
S449
G
D
G
E
L
D
L
S
G
I
D
D
L
E
I
Rat
Rattus norvegicus
NP_001100231
686
74096
S459
G
D
G
E
L
D
L
S
G
I
D
D
L
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421405
681
75256
S455
G
D
G
E
L
D
L
S
G
I
D
D
S
E
I
Frog
Xenopus laevis
NP_001088063
660
73751
N442
G
D
G
E
L
D
L
N
G
I
D
D
N
E
I
Zebra Danio
Brachydanio rerio
NP_956183
693
76806
S449
T
T
N
V
E
E
K
S
D
S
G
E
L
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650616
662
73627
V448
D
D
E
L
D
Q
Y
V
L
T
E
E
E
S
V
Honey Bee
Apis mellifera
XP_623775
648
73504
L434
A
D
L
D
D
E
E
L
D
S
Y
I
M
S
E
Nematode Worm
Caenorhab. elegans
NP_495526
759
84015
E448
I
D
S
Y
I
L
T
E
S
E
V
A
I
K
T
Sea Urchin
Strong. purpuratus
XP_794011
768
83924
T517
D
D
G
E
L
D
L
T
G
I
D
E
K
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29056
596
66888
E382
T
R
K
R
K
L
S
E
V
S
I
Q
N
E
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
86.4
82.7
N.A.
89.8
81.6
N.A.
N.A.
78.1
72.5
65.9
N.A.
42.5
43.4
32.4
46.3
Protein Similarity:
100
80
87
85.9
N.A.
93.3
86
N.A.
N.A.
87
84.7
77.6
N.A.
59.6
61.7
50
60.1
P-Site Identity:
100
100
6.6
0
N.A.
100
100
N.A.
N.A.
93.3
86.6
13.3
N.A.
6.6
6.6
6.6
66.6
P-Site Similarity:
100
100
20
33.3
N.A.
100
100
N.A.
N.A.
93.3
93.3
40
N.A.
26.6
26.6
26.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
8
15
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
72
8
15
15
50
0
0
15
0
50
43
0
8
0
% D
% Glu:
8
8
8
50
8
15
8
15
8
15
15
29
8
58
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
43
0
50
0
0
0
0
0
50
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
8
8
0
8
8
8
0
0
50
8
8
8
0
43
% I
% Lys:
0
0
8
0
8
0
8
0
0
0
0
0
8
8
8
% K
% Leu:
8
0
8
8
50
15
58
15
8
0
0
0
36
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
8
0
0
0
0
15
8
0
0
0
15
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
8
0
15
8
0
0
0
0
0
0
0
8
8
0
% R
% Ser:
0
0
8
0
0
0
8
43
8
29
0
0
8
15
0
% S
% Thr:
15
8
0
0
0
0
8
8
0
8
0
0
0
0
8
% T
% Val:
0
0
0
8
0
0
0
8
8
0
8
0
0
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
8
8
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _