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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 16.97
Human Site: S47 Identified Species: 28.72
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S47 E V Q F V E S S G G G S S A V
Chimpanzee Pan troglodytes XP_510208 819 88957 Q189 E R C S R G E Q R R G S S X X
Rhesus Macaque Macaca mulatta XP_001098066 599 65136
Dog Lupus familis XP_548005 637 70371 Q44 L G K E S R A Q T L Q N G R R
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 S47 E V Q F V E N S G G G S S A V
Rat Rattus norvegicus NP_001100231 686 74096 S47 E V Q F V E N S G G G S S A V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 S48 E V Q F V E N S G G G S S A V
Frog Xenopus laevis NP_001088063 660 73751 A47 E V Q F V E G A G G V S S A V
Zebra Danio Brachydanio rerio NP_956183 693 76806 G54 G G V S S A V G Q F V S A D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 G48 E V Q F E E V G H G A A A I G
Honey Bee Apis mellifera XP_623775 648 73504 P47 E T A F K E T P S G N M M V L
Nematode Worm Caenorhab. elegans NP_495526 759 84015 G47 N Q F Q E R A G G S G H T L V
Sea Urchin Strong. purpuratus XP_794011 768 83924 T48 E V G F A E N T L G G T S V I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 26.6 0 0 N.A. 93.3 93.3 N.A. N.A. 93.3 80 6.6 N.A. 40 26.6 20 46.6
P-Site Similarity: 100 26.6 0 20 N.A. 100 100 N.A. N.A. 100 86.6 13.3 N.A. 53.3 40 33.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 8 15 8 0 0 8 8 15 36 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 65 0 0 8 15 58 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 58 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 8 15 8 0 0 8 8 22 43 58 50 0 8 0 15 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % I
% Lys: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 0 0 0 0 0 8 8 0 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % M
% Asn: 8 0 0 0 0 0 29 0 0 0 8 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 8 43 8 0 0 0 15 8 0 8 0 0 0 0 % Q
% Arg: 0 8 0 0 8 15 0 0 8 8 0 0 0 8 8 % R
% Ser: 0 0 0 15 15 0 8 29 8 8 0 50 50 0 0 % S
% Thr: 0 8 0 0 0 0 8 8 8 0 0 8 8 0 0 % T
% Val: 0 50 8 0 36 0 15 0 0 0 15 0 0 15 43 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _