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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 18.18
Human Site: S548 Identified Species: 30.77
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S548 S V L R G L S S A G G G S P H
Chimpanzee Pan troglodytes XP_510208 819 88957 S690 S V L R G L S S A G G G S P H
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 H477 S A G G G S P H R E D A Q P E
Dog Lupus familis XP_548005 637 70371 V515 N S K G G G S V P G E D T R A
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 S547 S V L R D L N S K G G G S P P
Rat Rattus norvegicus NP_001100231 686 74096 S557 S V L R D L N S K G G G S P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 S553 N V L R D L N S K G S N T P K
Frog Xenopus laevis NP_001088063 660 73751 L535 S K I N Y D V L R D L N S K G
Zebra Danio Brachydanio rerio NP_956183 693 76806 S554 D V L R D L N S K G S A S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 D540 D G M G G L T D D S P T T S A
Honey Bee Apis mellifera XP_623775 648 73504 S526 V L K S L N V S L N T S T K E
Nematode Worm Caenorhab. elegans NP_495526 759 84015 K584 A S E S T I Q K L R S I F D L
Sea Urchin Strong. purpuratus XP_794011 768 83924 Q617 D V L R D L T Q P S P S H K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 L474 D E E L N A H L L N E E A S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 20 20 N.A. 73.3 73.3 N.A. N.A. 46.6 13.3 46.6 N.A. 13.3 6.6 0 26.6
P-Site Similarity: 100 100 20 33.3 N.A. 80 80 N.A. N.A. 66.6 20 53.3 N.A. 33.3 20 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 0 0 8 0 0 15 0 0 15 8 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 29 0 0 0 36 8 0 8 8 8 8 8 0 8 0 % D
% Glu: 0 8 15 0 0 0 0 0 0 8 15 8 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 0 8 8 22 36 8 0 0 0 50 29 29 0 0 8 % G
% His: 0 0 0 0 0 0 8 8 0 0 0 0 8 0 15 % H
% Ile: 0 0 8 0 0 8 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 8 15 0 0 0 0 8 29 0 0 0 0 22 15 % K
% Leu: 0 8 50 8 8 58 0 15 22 0 8 0 0 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 0 0 8 8 8 29 0 0 15 0 15 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 15 0 15 0 0 43 22 % P
% Gln: 0 0 0 0 0 0 8 8 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 50 0 0 0 0 15 8 0 0 0 8 0 % R
% Ser: 43 15 0 15 0 8 22 50 0 15 22 15 43 22 8 % S
% Thr: 0 0 0 0 8 0 15 0 0 0 8 8 29 0 0 % T
% Val: 8 50 0 0 0 0 15 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _