Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 22.12
Human Site: S553 Identified Species: 37.44
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S553 L S S A G G G S P H R E D A Q
Chimpanzee Pan troglodytes XP_510208 819 88957 S695 L S S A G G G S P H R E D A Q
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 Q482 S P H R E D A Q P E H S T S A
Dog Lupus familis XP_548005 637 70371 T520 G S V P G E D T R A E E R A S
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 S552 L N S K G G G S P P R D D S Q
Rat Rattus norvegicus NP_001100231 686 74096 S562 L N S K G G G S P P R D D S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 T558 L N S K G S N T P K K E D D S
Frog Xenopus laevis NP_001088063 660 73751 S540 D V L R D L N S K G S S T P K
Zebra Danio Brachydanio rerio NP_956183 693 76806 S559 L N S K G S A S S S T Q Q A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 T545 L T D D S P T T S A D T K P S
Honey Bee Apis mellifera XP_623775 648 73504 T531 N V S L N T S T K E Q Q K I E
Nematode Worm Caenorhab. elegans NP_495526 759 84015 F589 I Q K L R S I F D L T E E C S
Sea Urchin Strong. purpuratus XP_794011 768 83924 H622 L T Q P S P S H K P S Q P S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 A479 A H L L N E E A S K L K E R I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 6.6 26.6 N.A. 66.6 66.6 N.A. N.A. 40 6.6 33.3 N.A. 6.6 6.6 6.6 13.3
P-Site Similarity: 100 100 13.3 33.3 N.A. 86.6 86.6 N.A. N.A. 60 13.3 53.3 N.A. 20 33.3 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 15 0 0 15 8 0 15 0 0 0 29 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 0 8 8 8 8 8 0 8 0 8 15 36 8 0 % D
% Glu: 0 0 0 0 8 15 8 0 0 15 8 36 15 0 15 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 50 29 29 0 0 8 0 0 0 0 0 % G
% His: 0 8 8 0 0 0 0 8 0 15 8 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 0 0 0 0 0 8 8 % I
% Lys: 0 0 8 29 0 0 0 0 22 15 8 8 15 0 8 % K
% Leu: 58 0 15 22 0 8 0 0 0 8 8 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 29 0 0 15 0 15 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 15 0 15 0 0 43 22 0 0 8 15 0 % P
% Gln: 0 8 8 0 0 0 0 8 0 0 8 22 8 0 36 % Q
% Arg: 0 0 0 15 8 0 0 0 8 0 29 0 8 8 0 % R
% Ser: 8 22 50 0 15 22 15 43 22 8 15 15 0 29 29 % S
% Thr: 0 15 0 0 0 8 8 29 0 0 15 8 15 0 0 % T
% Val: 0 15 8 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _