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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 14.24
Human Site: S566 Identified Species: 24.1
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S566 A Q P E H S A S A R K L S R R
Chimpanzee Pan troglodytes XP_510208 819 88957 S708 A Q P E H S A S A R K L S R R
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 R495 S A R K L S R R R T P A S R S
Dog Lupus familis XP_548005 637 70371 R533 A S A R K L S R R K T P A S R
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 S565 S Q P P E R A S T K K L S R R
Rat Rattus norvegicus NP_001100231 686 74096 S575 S Q P P E H T S T K K L S R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 N571 D S T D D S T N T K K L S R R
Frog Xenopus laevis NP_001088063 660 73751 M553 P K Q D K N D M E D G I N S N
Zebra Danio Brachydanio rerio NP_956183 693 76806 G572 A E D V P T S G S G R K R L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 K558 P S T L E E L K H Q P V I V E
Honey Bee Apis mellifera XP_623775 648 73504 S544 I E E S I Q P S K I E I N N I
Nematode Worm Caenorhab. elegans NP_495526 759 84015 S602 C S E T S K N S S P K V N L K
Sea Urchin Strong. purpuratus XP_794011 768 83924 P635 S Q L A E T S P S V N L S T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 A492 R I W I G L N A D F L L E Q E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 20 13.3 N.A. 60 53.3 N.A. N.A. 40 0 6.6 N.A. 0 6.6 13.3 20
P-Site Similarity: 100 100 33.3 33.3 N.A. 73.3 66.6 N.A. N.A. 60 33.3 40 N.A. 13.3 33.3 40 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 8 8 8 0 0 22 8 15 0 0 8 8 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 15 8 0 8 0 8 8 0 0 0 0 0 % D
% Glu: 0 15 15 15 29 8 0 0 8 0 8 0 8 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 8 0 8 8 0 0 0 0 % G
% His: 0 0 0 0 15 8 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 8 0 8 8 0 0 0 0 8 0 15 8 0 8 % I
% Lys: 0 8 0 8 15 8 0 8 8 29 43 8 0 0 8 % K
% Leu: 0 0 8 8 8 15 8 0 0 0 8 50 0 15 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 15 8 0 0 8 0 22 8 8 % N
% Pro: 15 0 29 15 8 0 8 8 0 8 15 8 0 0 8 % P
% Gln: 0 36 8 0 0 8 0 0 0 8 0 0 0 8 0 % Q
% Arg: 8 0 8 8 0 8 8 15 15 15 8 0 8 43 43 % R
% Ser: 29 29 0 8 8 29 22 43 22 0 0 0 50 15 8 % S
% Thr: 0 0 15 8 0 15 15 0 22 8 8 0 0 8 8 % T
% Val: 0 0 0 8 0 0 0 0 0 8 0 15 0 8 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _