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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 16.67
Human Site: S571 Identified Species: 28.21
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S571 S A S A R K L S R R R T P A S
Chimpanzee Pan troglodytes XP_510208 819 88957 S713 S A S A R K L S R R R T P A S
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 S500 S R R R T P A S R S G A D P V
Dog Lupus familis XP_548005 637 70371 A538 L S R R K T P A S R S G A D P
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 S570 R A S T K K L S R R K R A T T
Rat Rattus norvegicus NP_001100231 686 74096 S580 H T S T K K L S R R K R A A T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 S576 S T N T K K L S R R K S I A S
Frog Xenopus laevis NP_001088063 660 73751 N558 N D M E D G I N S N Q L S R R
Zebra Danio Brachydanio rerio NP_956183 693 76806 R577 T S G S G R K R L T R R K K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 I563 E L K H Q P V I V E E G P V A
Honey Bee Apis mellifera XP_623775 648 73504 N549 Q P S K I E I N N I A S S N K
Nematode Worm Caenorhab. elegans NP_495526 759 84015 N607 K N S S P K V N L K V E S A S
Sea Urchin Strong. purpuratus XP_794011 768 83924 S640 T S P S V N L S T P F R A G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 E497 L N A D F L L E Q E S K R L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 20 6.6 N.A. 46.6 46.6 N.A. N.A. 53.3 0 6.6 N.A. 6.6 6.6 26.6 13.3
P-Site Similarity: 100 100 20 26.6 N.A. 66.6 66.6 N.A. N.A. 80 26.6 33.3 N.A. 26.6 33.3 53.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 8 15 0 0 8 8 0 0 8 8 29 36 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 8 0 0 0 0 0 0 0 8 8 0 % D
% Glu: 8 0 0 8 0 8 0 8 0 15 8 8 0 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 8 0 8 8 0 0 0 0 8 15 0 8 8 % G
% His: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 15 8 0 8 0 0 8 0 0 % I
% Lys: 8 0 8 8 29 43 8 0 0 8 22 8 8 8 15 % K
% Leu: 15 8 0 0 0 8 50 0 15 0 0 8 0 8 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 15 8 0 0 8 0 22 8 8 0 0 0 8 0 % N
% Pro: 0 8 8 0 8 15 8 0 0 8 0 0 22 8 8 % P
% Gln: 8 0 0 0 8 0 0 0 8 0 8 0 0 0 8 % Q
% Arg: 8 8 15 15 15 8 0 8 43 43 22 29 8 8 8 % R
% Ser: 29 22 43 22 0 0 0 50 15 8 15 15 22 0 29 % S
% Thr: 15 15 0 22 8 8 0 0 8 8 0 15 0 8 15 % T
% Val: 0 0 0 0 8 0 15 0 8 0 8 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _