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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 31.52
Human Site: Y481 Identified Species: 53.33
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 Y481 W M R E N A E Y L R E Q R E K
Chimpanzee Pan troglodytes XP_510208 819 88957 Y623 W M R E N A E Y L R E Q R E K
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 A415 R E K E A R I A K E K E L G I
Dog Lupus familis XP_548005 637 70371 I453 Q R E K E A R I A K E K E L G
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 Y480 W M R E N A E Y L R E Q K E K
Rat Rattus norvegicus NP_001100231 686 74096 Y490 W M R E N A E Y L R E Q K E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 Y486 W M K E N A D Y L K E Q K E K
Frog Xenopus laevis NP_001088063 660 73751 Y473 W M K E N A D Y L R E Q K E K
Zebra Danio Brachydanio rerio NP_956183 693 76806 Y488 W M K Q N E E Y L R E Q K E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 R478 E Q K E R D E R L A K E R E E
Honey Bee Apis mellifera XP_623775 648 73504 E464 E Y L I Q Q K E R E E K R Q K
Nematode Worm Caenorhab. elegans NP_495526 759 84015 G481 R E R E L N G G V K K K K P R
Sea Urchin Strong. purpuratus XP_794011 768 83924 Y548 W M K E N G E Y M K L M E E K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 S412 K K V K T K T S E E K K E N E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 6.6 13.3 N.A. 93.3 93.3 N.A. N.A. 73.3 80 73.3 N.A. 33.3 20 13.3 53.3
P-Site Similarity: 100 100 26.6 33.3 N.A. 100 100 N.A. N.A. 100 100 93.3 N.A. 60 40 53.3 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 50 0 8 8 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 15 0 0 0 0 0 0 0 0 % D
% Glu: 15 15 8 72 8 8 50 8 8 22 65 15 22 65 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 8 8 0 0 0 0 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 8 8 0 0 0 0 0 0 8 % I
% Lys: 8 8 43 15 0 8 8 0 8 29 29 29 43 0 65 % K
% Leu: 0 0 8 0 8 0 0 0 58 0 8 0 8 8 0 % L
% Met: 0 58 0 0 0 0 0 0 8 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 58 8 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % P
% Gln: 8 8 0 8 8 8 0 0 0 0 0 50 0 8 0 % Q
% Arg: 15 8 36 0 8 8 8 8 8 43 0 0 29 0 8 % R
% Ser: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % V
% Trp: 58 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 58 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _