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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP13
All Species:
26.97
Human Site:
Y374
Identified Species:
49.44
UniProt:
Q92995
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92995
NP_003931.2
863
97327
Y374
N
L
P
R
I
F
D
Y
S
P
L
D
P
T
Q
Chimpanzee
Pan troglodytes
XP_526393
1007
112608
Y527
N
L
P
R
I
F
D
Y
S
P
L
D
P
T
Q
Rhesus Macaque
Macaca mulatta
XP_001107760
863
97273
Y374
N
L
P
R
I
F
D
Y
S
P
L
D
P
T
Q
Dog
Lupus familis
XP_535813
863
97440
Y374
N
L
P
R
I
F
D
Y
S
P
L
D
P
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
P56399
858
95815
N364
K
L
E
K
I
F
Q
N
A
P
T
D
P
T
Q
Rat
Rattus norvegicus
NP_001101135
858
96730
Y372
N
L
P
R
I
F
D
Y
S
P
L
D
P
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426842
862
96630
Y369
N
L
P
R
I
F
D
Y
S
P
L
D
P
T
Q
Frog
Xenopus laevis
NP_001083082
832
92955
K363
R
M
E
H
I
F
R
K
S
P
A
D
P
T
Q
Zebra Danio
Brachydanio rerio
NP_001091856
860
97461
Y356
N
L
Q
R
I
F
D
Y
S
P
L
D
P
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624702
793
90372
I347
P
D
F
I
K
R
F
I
D
G
A
S
Q
I
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189314
790
88932
F351
A
S
K
K
D
E
I
F
T
S
A
P
A
D
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Y1
797
88355
F346
H
Q
S
L
K
M
A
F
E
M
A
P
A
D
P
Baker's Yeast
Sacchar. cerevisiae
P38237
781
88611
V342
N
S
V
I
Q
S
L
V
N
G
G
V
P
N
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.5
99.5
98.2
N.A.
61
95.7
N.A.
N.A.
83.8
58.1
74.7
N.A.
N.A.
44.7
N.A.
47.5
Protein Similarity:
100
84.6
99.7
99.3
N.A.
77.7
97.8
N.A.
N.A.
92.2
74.6
86.6
N.A.
N.A.
63.6
N.A.
66.2
P-Site Identity:
100
100
100
100
N.A.
53.3
100
N.A.
N.A.
100
53.3
93.3
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
66.6
100
N.A.
N.A.
100
60
93.3
N.A.
N.A.
0
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.7
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.5
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
8
0
31
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
54
0
8
0
0
70
0
16
0
% D
% Glu:
0
0
16
0
0
8
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
70
8
16
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
16
8
0
0
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
16
70
0
8
8
0
0
0
0
0
8
0
% I
% Lys:
8
0
8
16
16
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
62
0
8
0
0
8
0
0
0
54
0
0
0
0
% L
% Met:
0
8
0
0
0
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
62
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% N
% Pro:
8
0
47
0
0
0
0
0
0
70
0
16
77
0
16
% P
% Gln:
0
8
8
0
8
0
8
0
0
0
0
0
8
0
70
% Q
% Arg:
8
0
0
54
0
8
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
16
8
0
0
8
0
0
62
8
0
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
0
8
0
0
70
0
% T
% Val:
0
0
8
0
0
0
0
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _