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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP13
All Species:
36.36
Human Site:
Y580
Identified Species:
66.67
UniProt:
Q92995
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92995
NP_003931.2
863
97327
Y580
R
F
A
S
F
P
E
Y
L
V
V
Q
I
K
K
Chimpanzee
Pan troglodytes
XP_526393
1007
112608
Y733
R
F
A
S
F
P
E
Y
L
V
V
Q
I
K
K
Rhesus Macaque
Macaca mulatta
XP_001107760
863
97273
Y580
R
F
A
S
F
P
E
Y
L
V
V
Q
I
K
K
Dog
Lupus familis
XP_535813
863
97440
Y580
R
F
A
S
F
P
E
Y
L
V
V
Q
I
K
K
Cat
Felis silvestris
Mouse
Mus musculus
P56399
858
95815
Y568
R
F
A
S
F
P
D
Y
L
V
I
Q
I
K
K
Rat
Rattus norvegicus
NP_001101135
858
96730
Y578
R
F
A
S
F
P
E
Y
L
V
V
Q
I
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426842
862
96630
Y575
R
F
A
S
F
P
Q
Y
L
V
V
Q
I
K
K
Frog
Xenopus laevis
NP_001083082
832
92955
Y566
R
F
A
S
F
P
D
Y
L
V
I
Q
I
K
K
Zebra Danio
Brachydanio rerio
NP_001091856
860
97461
Y563
R
F
A
T
F
P
E
Y
M
I
V
Q
L
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624702
793
90372
A536
V
E
Q
F
Y
S
S
A
L
N
E
K
T
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189314
790
88932
A537
K
V
E
D
F
Y
S
A
A
I
N
A
K
T
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L6Y1
797
88355
K542
K
G
M
T
T
A
I
K
T
T
G
L
T
S
F
Baker's Yeast
Sacchar. cerevisiae
P38237
781
88611
P527
P
Q
T
L
I
L
N
P
I
R
I
R
L
Q
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.5
99.5
98.2
N.A.
61
95.7
N.A.
N.A.
83.8
58.1
74.7
N.A.
N.A.
44.7
N.A.
47.5
Protein Similarity:
100
84.6
99.7
99.3
N.A.
77.7
97.8
N.A.
N.A.
92.2
74.6
86.6
N.A.
N.A.
63.6
N.A.
66.2
P-Site Identity:
100
100
100
100
N.A.
86.6
100
N.A.
N.A.
93.3
86.6
73.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.7
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
61.5
45
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
70
0
0
8
0
16
8
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
16
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
8
0
0
0
47
0
0
0
8
0
0
0
0
% E
% Phe:
0
70
0
8
77
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
8
16
24
0
62
0
0
% I
% Lys:
16
0
0
0
0
0
0
8
0
0
0
8
8
70
70
% K
% Leu:
0
0
0
8
0
8
0
0
70
0
0
8
16
0
0
% L
% Met:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
8
8
0
0
0
8
% N
% Pro:
8
0
0
0
0
70
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
8
0
0
0
0
70
0
8
0
% Q
% Arg:
70
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
0
0
0
62
0
8
16
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
8
16
8
0
0
0
8
8
0
0
16
16
0
% T
% Val:
8
8
0
0
0
0
0
0
0
62
54
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
8
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _