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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DVL3 All Species: 25.15
Human Site: S573 Identified Species: 61.48
UniProt: Q92997 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92997 NP_004414.3 716 78055 S573 S S Q H S E G S R S S G S N R
Chimpanzee Pan troglodytes Q5IS48 670 72833 T540 F S Y G S G S T G S Q Q S E G
Rhesus Macaque Macaca mulatta XP_001094101 740 79711 S597 S S Q H S E G S R S S G S N R
Dog Lupus familis XP_535822 716 78058 S573 S S Q H S E G S R S S G S N R
Cat Felis silvestris
Mouse Mus musculus Q61062 716 78104 S573 S S Q H S E G S R S S G S N R
Rat Rattus norvegicus Q9WVB9 695 75429 P556 F P P A Y Q D P G F S Y G S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422756 833 90624 S694 G S Q H S E G S R S S G S N R
Frog Xenopus laevis Q6DKE2 717 78751 S571 G S Q H S E G S R S S G S N R
Zebra Danio Brachydanio rerio NP_571832 676 73906 Y546 P A A F P Y Q Y P A A H S H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P51140 623 68898 H493 G R G H L H P H Q L P H G H G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.8 90.9 99.3 N.A. 98.7 66.4 N.A. N.A. 75 85.3 69.6 N.A. 42.4 N.A. N.A. N.A.
Protein Similarity: 100 76.8 92.8 99.7 N.A. 99 79.4 N.A. N.A. 80.4 92.3 78 N.A. 56.9 N.A. N.A. N.A.
P-Site Identity: 100 26.6 100 100 N.A. 100 6.6 N.A. N.A. 93.3 93.3 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 100 20 N.A. N.A. 93.3 93.3 33.3 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 0 0 0 0 0 10 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 60 0 0 0 0 0 0 0 10 0 % E
% Phe: 20 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 30 0 10 10 0 10 60 0 20 0 0 60 20 0 30 % G
% His: 0 0 0 70 0 10 0 10 0 0 0 20 0 20 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 10 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 60 0 % N
% Pro: 10 10 10 0 10 0 10 10 10 0 10 0 0 0 0 % P
% Gln: 0 0 60 0 0 10 10 0 10 0 10 10 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 60 0 0 0 0 0 60 % R
% Ser: 40 70 0 0 70 0 10 60 0 70 70 0 80 10 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 10 10 0 10 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _