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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP7 All Species: 43.94
Human Site: T211 Identified Species: 69.05
UniProt: Q93009 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93009 NP_003461.2 1102 128302 T211 A W D S K K H T G Y V G L K N
Chimpanzee Pan troglodytes XP_510806 1102 128297 T211 A W D S K K H T G Y V G L K N
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536979 1086 126326 T195 A W D S K K H T G Y V G L K N
Cat Felis silvestris
Mouse Mus musculus Q6A4J8 1103 128457 T212 A W D S K K H T G Y V G L K N
Rat Rattus norvegicus Q4VSI4 1103 128413 T212 A W D S K K H T G Y V G L K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506396 1145 132881 T254 A W D S K K H T G Y V G L K N
Chicken Gallus gallus Q6U7I1 1101 128279 T211 A W D S K K H T G Y V G L K N
Frog Xenopus laevis NP_001121282 534 61718
Zebra Danio Brachydanio rerio XP_691215 1103 128646 T212 A W D S K K H T G Y V G L K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VYQ8 1129 130428 T238 L W D S K K H T G Y V G L K N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q7JKC3 1135 131579 G199 C I G L R N Q G A T C Y M N S
Sea Urchin Strong. purpuratus XP_780569 1189 136707 T307 S W D S K K L T G Y V G L K N
Poplar Tree Populus trichocarpa XP_002316470 1116 130731 G195 H D S K K E T G Y V G L K N Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WU2 1115 130630 G196 Y D S K K E T G F V G L K N Q
Baker's Yeast Sacchar. cerevisiae P50101 1230 143545 T202 N Y D S K K V T G Y V G F R N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 97.7 N.A. 99 99 N.A. 92.4 95.9 46 94 N.A. 48.5 N.A. 34.4 54.5
Protein Similarity: 100 99.9 N.A. 98 N.A. 99.7 99.8 N.A. 94.7 97.9 47.4 96.8 N.A. 67.5 N.A. 52.5 69.2
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 0 100 N.A. 93.3 N.A. 0 86.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 0 100 N.A. 93.3 N.A. 20 93.3
Percent
Protein Identity: 36.9 N.A. N.A. 36.5 29.4 N.A.
Protein Similarity: 54.3 N.A. N.A. 54.7 47.8 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 66.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 54 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 0 14 74 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 7 0 0 0 7 0 0 % F
% Gly: 0 0 7 0 0 0 0 20 74 0 14 74 0 0 0 % G
% His: 7 0 0 0 0 0 60 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 14 87 74 0 0 0 0 0 0 14 67 0 % K
% Leu: 7 0 0 7 0 0 7 0 0 0 0 14 67 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 7 0 0 0 0 7 0 0 0 0 0 0 0 20 74 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 14 % Q
% Arg: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % R
% Ser: 7 0 14 74 0 0 0 0 0 0 0 0 0 0 7 % S
% Thr: 0 0 0 0 0 0 14 74 0 7 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 7 0 0 14 74 0 0 0 0 % V
% Trp: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 7 0 0 0 0 0 0 7 74 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _