Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP7 All Species: 16.97
Human Site: T30 Identified Species: 26.67
UniProt: Q93009 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93009 NP_003461.2 1102 128302 T30 M E M E A G D T D D P P R I T
Chimpanzee Pan troglodytes XP_510806 1102 128297 T30 M E M E A G D T D D P P R I T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536979 1086 126326 I20 D T D D P P R I T Q N P V I N
Cat Felis silvestris
Mouse Mus musculus Q6A4J8 1103 128457 T31 M E M E A G D T D D P P R I T
Rat Rattus norvegicus Q4VSI4 1103 128413 T31 M E M E A G D T D D P P R I T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506396 1145 132881 T73 P C R S A G D T D D P P R I T
Chicken Gallus gallus Q6U7I1 1101 128279 A30 M E M E A G D A D D P P R I T
Frog Xenopus laevis NP_001121282 534 61718
Zebra Danio Brachydanio rerio XP_691215 1103 128646 P31 M E M E A G D P D D P P R I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VYQ8 1129 130428 F43 S P P Q L P K F K N L I Q P Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q7JKC3 1135 131579 E23 H D I P S Y D E S L D P F G P
Sea Urchin Strong. purpuratus XP_780569 1189 136707 K122 V E L R E S D K K K S K K T N
Poplar Tree Populus trichocarpa XP_002316470 1116 130731 P20 E D D E M L V P H T E F T E G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84WU2 1115 130630 P20 E D E E M L V P N P D L V E G
Baker's Yeast Sacchar. cerevisiae P50101 1230 143545 I26 I D K S I G S I L P Q F D E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 97.7 N.A. 99 99 N.A. 92.4 95.9 46 94 N.A. 48.5 N.A. 34.4 54.5
Protein Similarity: 100 99.9 N.A. 98 N.A. 99.7 99.8 N.A. 94.7 97.9 47.4 96.8 N.A. 67.5 N.A. 52.5 69.2
P-Site Identity: 100 100 N.A. 13.3 N.A. 100 100 N.A. 73.3 93.3 0 86.6 N.A. 0 N.A. 13.3 13.3
P-Site Similarity: 100 100 N.A. 20 N.A. 100 100 N.A. 73.3 93.3 0 86.6 N.A. 20 N.A. 33.3 33.3
Percent
Protein Identity: 36.9 N.A. N.A. 36.5 29.4 N.A.
Protein Similarity: 54.3 N.A. N.A. 54.7 47.8 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: 13.3 N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 47 0 0 7 0 0 0 0 0 0 0 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 27 14 7 0 0 60 0 47 47 14 0 7 0 0 % D
% Glu: 14 47 7 54 7 0 0 7 0 0 7 0 0 20 7 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 14 7 0 0 % F
% Gly: 0 0 0 0 0 54 0 0 0 0 0 0 0 7 14 % G
% His: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 7 0 7 0 7 0 0 14 0 0 0 7 0 54 0 % I
% Lys: 0 0 7 0 0 0 7 7 14 7 0 7 7 0 0 % K
% Leu: 0 0 7 0 7 14 0 0 7 7 7 7 0 0 0 % L
% Met: 40 0 40 0 14 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 7 7 0 0 0 14 % N
% Pro: 7 7 7 7 7 14 0 20 0 14 47 60 0 7 14 % P
% Gln: 0 0 0 7 0 0 0 0 0 7 7 0 7 0 7 % Q
% Arg: 0 0 7 7 0 0 7 0 0 0 0 0 47 0 0 % R
% Ser: 7 0 0 14 7 7 7 0 7 0 7 0 0 0 0 % S
% Thr: 0 7 0 0 0 0 0 34 7 7 0 0 7 7 40 % T
% Val: 7 0 0 0 0 0 14 0 0 0 0 0 14 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _