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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
32.73
Human Site:
S133
Identified Species:
51.43
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
S133
K
K
S
N
V
E
D
S
I
V
R
K
L
M
L
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
D114
E
R
L
G
E
A
F
D
S
Q
L
V
I
G
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
S164
K
K
S
T
V
E
D
S
I
V
R
K
L
M
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
S133
K
K
S
N
M
E
D
S
I
V
R
K
L
M
L
Rat
Rattus norvegicus
Q9JJ31
780
90872
S133
K
K
S
N
M
E
D
S
I
V
R
K
L
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
S132
K
K
S
N
V
E
D
S
I
V
R
K
L
M
L
Chicken
Gallus gallus
XP_417163
809
94020
S162
K
K
S
N
V
E
D
S
I
V
R
K
L
M
L
Frog
Xenopus laevis
Q6GPF3
768
88937
Y125
M
I
R
D
I
L
M
Y
M
D
R
V
Y
V
Q
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
S133
K
K
S
N
V
E
D
S
I
V
R
K
L
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
S121
W
K
S
Y
Q
F
S
S
T
V
L
D
G
I
C
Honey Bee
Apis mellifera
XP_623958
789
91733
D135
V
Q
K
K
S
Q
P
D
D
I
V
R
K
L
M
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
E117
S
V
P
E
T
P
E
E
S
I
R
T
V
M
L
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
N145
Q
K
K
A
N
Q
Q
N
E
D
S
T
V
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
Y118
F
F
Y
Y
L
D
R
Y
F
I
A
R
R
S
L
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
Y137
A
F
D
Y
M
N
R
Y
W
V
Q
K
E
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
0
N.A.
93.3
N.A.
93.3
93.3
N.A.
100
100
6.6
100
N.A.
26.6
0
20
6.6
P-Site Similarity:
100
26.6
N.A.
93.3
N.A.
100
100
N.A.
100
100
33.3
100
N.A.
33.3
40
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
7
0
0
0
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
7
7
0
7
47
14
7
14
0
7
0
0
0
% D
% Glu:
7
0
0
7
7
47
7
7
7
0
0
0
7
0
0
% E
% Phe:
7
14
0
0
0
7
7
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
0
0
7
7
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
7
0
0
0
47
20
0
0
7
7
0
% I
% Lys:
47
60
14
7
0
0
0
0
0
0
0
54
7
0
7
% K
% Leu:
0
0
7
0
7
7
0
0
0
0
14
0
47
7
60
% L
% Met:
7
0
0
0
20
0
7
0
7
0
0
0
0
54
7
% M
% Asn:
0
0
0
40
7
7
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
7
7
0
0
0
0
0
0
0
0
% P
% Gln:
7
7
0
0
7
14
7
0
0
7
7
0
0
0
7
% Q
% Arg:
0
7
7
0
0
0
14
0
0
0
60
14
7
14
0
% R
% Ser:
7
0
54
0
7
0
7
54
14
0
7
0
0
7
7
% S
% Thr:
0
0
0
7
7
0
0
0
7
0
0
14
0
0
0
% T
% Val:
7
7
0
0
34
0
0
0
0
60
7
14
14
7
7
% V
% Trp:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
7
20
0
0
0
20
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _