KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
33.03
Human Site:
S257
Identified Species:
51.9
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
S257
E
T
R
R
E
C
N
S
V
E
A
L
M
E
C
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
L240
K
L
H
L
M
F
S
L
M
D
K
V
P
N
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
S288
E
T
R
R
E
C
N
S
V
E
A
L
M
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
S257
E
T
R
R
E
C
N
S
V
E
A
L
M
E
C
Rat
Rattus norvegicus
Q9JJ31
780
90872
S257
E
T
R
R
E
C
N
S
V
E
A
L
M
E
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
S256
E
T
R
R
E
C
N
S
V
E
A
L
M
E
C
Chicken
Gallus gallus
XP_417163
809
94020
S286
E
T
R
R
E
C
N
S
V
E
A
L
M
E
C
Frog
Xenopus laevis
Q6GPF3
768
88937
I260
D
K
S
T
E
E
P
I
V
K
V
V
E
R
E
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
S257
E
T
R
R
E
C
N
S
V
Q
A
L
M
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
V255
V
T
E
Y
L
K
H
V
E
N
R
L
E
E
E
Honey Bee
Apis mellifera
XP_623958
789
91733
Q260
E
P
N
S
A
S
V
Q
L
L
T
D
C
C
V
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
G242
E
M
N
S
P
T
S
G
K
H
M
E
K
A
V
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
S272
D
T
S
K
G
S
N
S
M
S
L
L
T
E
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
S243
A
H
Y
L
H
S
S
S
E
P
K
L
V
E
K
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
T275
T
I
Y
W
D
D
H
T
K
K
P
L
S
M
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
100
100
13.3
93.3
N.A.
20
6.6
6.6
40
P-Site Similarity:
100
33.3
N.A.
100
N.A.
100
100
N.A.
100
100
33.3
100
N.A.
26.6
13.3
13.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
7
0
0
0
0
0
47
0
0
7
7
% A
% Cys:
0
0
0
0
0
47
0
0
0
0
0
0
7
7
54
% C
% Asp:
14
0
0
0
7
7
0
0
0
7
0
7
0
0
0
% D
% Glu:
60
0
7
0
54
7
0
0
14
40
0
7
14
67
14
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
7
% G
% His:
0
7
7
0
7
0
14
0
0
7
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% I
% Lys:
7
7
0
7
0
7
0
0
14
14
14
0
7
0
7
% K
% Leu:
0
7
0
14
7
0
0
7
7
7
7
74
0
0
0
% L
% Met:
0
7
0
0
7
0
0
0
14
0
7
0
47
7
0
% M
% Asn:
0
0
14
0
0
0
54
0
0
7
0
0
0
7
0
% N
% Pro:
0
7
0
0
7
0
7
0
0
7
7
0
7
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% Q
% Arg:
0
0
47
47
0
0
0
0
0
0
7
0
0
7
0
% R
% Ser:
0
0
14
14
0
20
20
60
0
7
0
0
7
0
0
% S
% Thr:
7
60
0
7
0
7
0
7
0
0
7
0
7
0
0
% T
% Val:
7
0
0
0
0
0
7
7
54
0
7
14
7
0
14
% V
% Trp:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _