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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
39.09
Human Site:
S34
Identified Species:
61.43
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
S34
L
K
L
L
R
Q
E
S
V
T
K
Q
Q
W
F
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
S34
L
K
L
L
R
Q
E
S
V
T
K
Q
Q
W
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
S65
L
K
L
L
R
Q
E
S
V
T
K
Q
Q
W
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
S34
L
K
L
L
R
Q
E
S
V
T
K
Q
Q
W
F
Rat
Rattus norvegicus
Q9JJ31
780
90872
S34
L
K
L
L
R
Q
E
S
V
T
K
Q
Q
W
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
S33
L
K
L
L
R
Q
E
S
V
T
K
Q
Q
W
F
Chicken
Gallus gallus
XP_417163
809
94020
S63
L
K
L
L
R
Q
E
S
V
T
K
Q
Q
W
F
Frog
Xenopus laevis
Q6GPF3
768
88937
N48
I
Q
E
I
Q
R
K
N
N
S
G
L
S
F
E
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
S34
L
K
L
L
R
Q
E
S
V
T
K
Q
Q
W
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
S36
Q
V
F
E
H
E
K
S
L
T
R
S
Q
Y
M
Honey Bee
Apis mellifera
XP_623958
789
91733
T36
L
K
L
L
K
Q
E
T
V
T
Q
A
E
W
Q
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
T39
F
Y
H
V
Y
K
I
T
S
W
V
D
D
G
P
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
N46
L
K
L
L
R
Q
E
N
V
S
R
N
E
W
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
A33
L
E
G
L
N
E
P
A
F
D
S
E
Q
Y
M
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
I42
T
S
K
R
V
Y
K
I
L
S
P
T
M
Y
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
0
100
N.A.
20
60
0
60
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
60
100
N.A.
53.3
86.6
20
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
0
7
7
0
0
% D
% Glu:
0
7
7
7
0
14
67
0
0
0
0
7
14
0
7
% E
% Phe:
7
0
7
0
0
0
0
0
7
0
0
0
0
7
54
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
7
0
0
7
0
% G
% His:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
0
0
7
0
0
7
7
0
0
0
0
0
0
0
% I
% Lys:
0
67
7
0
7
7
20
0
0
0
54
0
0
0
0
% K
% Leu:
74
0
67
74
0
0
0
0
14
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
20
% M
% Asn:
0
0
0
0
7
0
0
14
7
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
7
% P
% Gln:
7
7
0
0
7
67
0
0
0
0
7
54
67
0
7
% Q
% Arg:
0
0
0
7
60
7
0
0
0
0
14
0
0
0
0
% R
% Ser:
0
7
0
0
0
0
0
60
7
20
7
7
7
0
0
% S
% Thr:
7
0
0
0
0
0
0
14
0
67
0
7
0
0
0
% T
% Val:
0
7
0
7
7
0
0
0
67
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
67
0
% W
% Tyr:
0
7
0
0
7
7
0
0
0
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _