KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
34.55
Human Site:
S730
Identified Species:
54.29
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
S730
M
K
M
R
K
K
I
S
N
A
Q
L
Q
T
E
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
N685
E
L
V
E
I
L
K
N
M
F
L
P
Q
K
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
S761
M
K
M
R
K
K
I
S
N
A
Q
L
Q
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
S730
M
K
M
R
K
K
I
S
N
A
Q
L
Q
T
E
Rat
Rattus norvegicus
Q9JJ31
780
90872
S730
M
K
M
R
K
K
I
S
N
A
Q
L
Q
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
T729
M
K
M
R
K
K
I
T
N
A
Q
L
Q
T
E
Chicken
Gallus gallus
XP_417163
809
94020
T759
M
K
M
R
K
K
I
T
N
A
Q
L
Q
T
E
Frog
Xenopus laevis
Q6GPF3
768
88937
Q718
M
K
S
R
K
K
M
Q
H
N
V
L
V
A
E
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
S730
M
K
M
R
K
R
I
S
N
A
Q
L
Q
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
N724
M
K
M
R
K
R
L
N
H
T
N
L
I
S
E
Honey Bee
Apis mellifera
XP_623958
789
91733
S739
L
K
M
R
K
K
I
S
N
A
Q
L
Q
T
E
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
T715
L
K
T
R
K
T
Y
T
L
A
Q
L
T
M
E
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
N737
M
K
M
R
K
K
L
N
N
A
Q
L
Q
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
L700
V
S
E
C
V
E
Q
L
S
R
M
F
K
P
D
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
P766
M
K
A
K
R
N
L
P
H
T
T
L
V
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
93.3
93.3
46.6
93.3
N.A.
46.6
93.3
46.6
86.6
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
100
N.A.
100
100
60
100
N.A.
80
100
60
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
67
0
0
0
7
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% D
% Glu:
7
0
7
7
0
7
0
0
0
0
0
0
0
0
87
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
0
54
0
0
0
0
0
7
0
0
% I
% Lys:
0
87
0
7
80
60
7
0
0
0
0
0
7
7
7
% K
% Leu:
14
7
0
0
0
7
20
7
7
0
7
87
0
0
0
% L
% Met:
74
0
67
0
0
0
7
0
7
0
7
0
0
7
0
% M
% Asn:
0
0
0
0
0
7
0
20
60
7
7
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
7
0
7
0
% P
% Gln:
0
0
0
0
0
0
7
7
0
0
67
0
67
0
0
% Q
% Arg:
0
0
0
80
7
14
0
0
0
7
0
0
0
0
0
% R
% Ser:
0
7
7
0
0
0
0
40
7
0
0
0
0
7
0
% S
% Thr:
0
0
7
0
0
7
0
20
0
14
7
0
7
60
0
% T
% Val:
7
0
7
0
7
0
0
0
0
0
7
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _