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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
40.3
Human Site:
T367
Identified Species:
63.33
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
T367
Q
D
D
P
R
F
L
T
A
R
D
K
A
Y
K
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
S343
G
L
K
T
Q
P
E
S
K
C
P
E
L
L
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
T398
Q
D
D
P
R
F
L
T
A
R
D
K
A
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
T367
Q
D
D
P
R
F
L
T
A
R
D
K
A
Y
K
Rat
Rattus norvegicus
Q9JJ31
780
90872
T367
Q
D
D
P
R
F
L
T
A
R
D
K
A
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
T366
Q
D
D
P
R
F
L
T
A
R
D
K
A
Y
K
Chicken
Gallus gallus
XP_417163
809
94020
T396
Q
D
D
P
R
F
L
T
A
R
D
K
A
Y
K
Frog
Xenopus laevis
Q6GPF3
768
88937
Q368
S
N
D
R
L
F
K
Q
T
I
A
G
D
F
E
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
T367
Q
D
D
P
R
F
L
T
S
R
D
K
A
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
D358
I
A
K
C
C
T
T
D
A
A
N
D
P
K
T
Honey Bee
Apis mellifera
XP_623958
789
91733
T368
D
D
D
P
R
F
L
T
A
R
D
K
A
Y
K
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
T350
C
D
D
A
R
L
L
T
A
R
D
K
A
F
R
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
T382
N
D
D
P
R
F
L
T
S
R
D
K
A
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
D347
R
K
V
I
E
L
H
D
K
Y
M
V
Y
V
T
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
L384
K
D
Y
I
K
K
L
L
E
V
H
D
I
F
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
100
100
13.3
93.3
N.A.
6.6
93.3
66.6
80
P-Site Similarity:
100
20
N.A.
100
N.A.
100
100
N.A.
100
100
33.3
100
N.A.
13.3
93.3
80
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
0
60
7
7
0
67
0
7
% A
% Cys:
7
0
0
7
7
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
7
74
74
0
0
0
0
14
0
0
67
14
7
0
0
% D
% Glu:
0
0
0
0
7
0
7
0
7
0
0
7
0
0
7
% E
% Phe:
0
0
0
0
0
67
0
0
0
0
0
0
0
20
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% H
% Ile:
7
0
0
14
0
0
0
0
0
7
0
0
7
0
0
% I
% Lys:
7
7
14
0
7
7
7
0
14
0
0
67
0
7
54
% K
% Leu:
0
7
0
0
7
14
74
7
0
0
0
0
7
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
60
0
7
0
0
0
0
7
0
7
0
0
% P
% Gln:
47
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
7
67
0
0
0
0
67
0
0
0
0
14
% R
% Ser:
7
0
0
0
0
0
0
7
14
0
0
0
0
0
7
% S
% Thr:
0
0
0
7
0
7
7
67
7
0
0
0
0
0
14
% T
% Val:
0
0
7
0
0
0
0
0
0
7
0
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
7
0
0
7
60
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _