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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
33.94
Human Site:
T419
Identified Species:
53.33
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
T419
C
D
M
L
L
R
K
T
P
L
S
K
K
L
T
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
K396
D
V
F
M
R
Y
H
K
A
H
L
T
R
R
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
T450
C
D
M
L
L
R
K
T
P
L
S
K
K
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
T419
C
D
M
L
L
R
K
T
P
L
S
K
K
L
T
Rat
Rattus norvegicus
Q9JJ31
780
90872
T419
C
D
M
L
L
R
K
T
P
L
S
K
K
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
T418
C
D
M
L
L
R
K
T
P
L
S
K
K
L
T
Chicken
Gallus gallus
XP_417163
809
94020
T448
C
D
M
L
L
R
K
T
P
L
S
K
K
L
T
Frog
Xenopus laevis
Q6GPF3
768
88937
K425
L
F
R
F
M
Q
E
K
D
V
F
E
R
Y
Y
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
T419
C
D
M
L
L
R
K
T
P
L
S
K
K
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
A414
V
V
T
I
A
N
S
A
S
K
S
P
E
L
L
Honey Bee
Apis mellifera
XP_623958
789
91733
T432
C
D
M
L
L
R
K
T
P
L
S
K
K
L
T
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
Q400
D
L
L
L
R
K
T
Q
L
S
K
K
L
T
S
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
P432
D
M
L
L
R
K
T
P
L
S
K
R
L
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
G399
C
D
N
I
L
K
K
G
G
S
E
K
L
S
D
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
S443
S
E
M
L
A
K
Y
S
D
I
L
L
K
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
100
100
0
100
N.A.
13.3
100
13.3
6.6
P-Site Similarity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
100
100
40
100
N.A.
26.6
100
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
14
0
0
7
7
0
0
0
0
0
7
% A
% Cys:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
60
0
0
0
0
0
0
14
0
0
0
0
0
7
% D
% Glu:
0
7
0
0
0
0
7
0
0
0
7
7
7
0
0
% E
% Phe:
0
7
7
7
0
0
0
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
14
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
27
60
14
0
7
14
67
60
7
0
% K
% Leu:
7
7
14
74
60
0
0
0
14
54
14
7
20
60
14
% L
% Met:
0
7
60
7
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
7
54
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
7
0
20
54
0
0
0
0
0
7
14
7
0
% R
% Ser:
7
0
0
0
0
0
7
7
7
20
60
0
0
7
14
% S
% Thr:
0
0
7
0
0
0
14
54
0
0
0
7
0
14
54
% T
% Val:
7
14
0
0
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
7
0
0
0
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _