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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
27.88
Human Site:
Y650
Identified Species:
43.81
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
Y650
L
K
R
Q
V
L
L
Y
E
P
Q
V
N
S
P
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
L615
S
V
N
Q
E
F
S
L
I
K
N
A
K
V
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
Y681
L
K
R
Q
V
L
L
Y
E
P
Q
V
N
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
Y650
L
K
R
Q
V
L
L
Y
D
P
Q
V
N
S
P
Rat
Rattus norvegicus
Q9JJ31
780
90872
Y650
L
K
R
Q
V
L
L
Y
D
P
Q
V
N
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
Y649
L
K
R
Q
V
L
L
Y
E
P
Q
V
N
S
P
Chicken
Gallus gallus
XP_417163
809
94020
Y679
L
K
R
Q
V
L
L
Y
E
P
Q
V
N
S
P
Frog
Xenopus laevis
Q6GPF3
768
88937
E647
T
Q
R
V
L
T
K
E
P
K
S
K
E
I
E
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
Y650
L
K
R
Q
V
L
S
Y
E
P
V
V
G
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
S655
K
A
K
V
L
T
S
S
D
N
E
N
S
L
T
Honey Bee
Apis mellifera
XP_623958
789
91733
V659
L
K
R
Q
L
L
L
V
E
P
H
A
H
S
P
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
C633
M
R
Y
Q
I
L
L
C
D
V
P
S
T
T
V
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
M657
L
K
R
Q
M
V
L
M
Q
P
E
A
K
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
N625
K
I
L
L
K
E
P
N
T
K
T
V
S
Q
N
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
L679
I
Q
Q
V
P
P
G
L
D
A
L
V
K
P
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
6.6
N.A.
100
N.A.
93.3
93.3
N.A.
100
100
6.6
80
N.A.
0
66.6
20
53.3
P-Site Similarity:
100
6.6
N.A.
100
N.A.
100
100
N.A.
100
100
20
80
N.A.
33.3
80
53.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
7
0
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
7
7
0
7
40
0
14
0
7
0
14
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% H
% Ile:
7
7
0
0
7
0
0
0
7
0
0
0
0
7
0
% I
% Lys:
14
60
7
0
7
0
7
0
0
20
0
7
20
0
0
% K
% Leu:
60
0
7
7
20
60
60
14
0
0
7
0
0
7
0
% L
% Met:
7
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
7
0
7
7
7
40
0
7
% N
% Pro:
0
0
0
0
7
7
7
0
7
60
7
0
0
7
60
% P
% Gln:
0
14
7
74
0
0
0
0
7
0
40
0
0
7
7
% Q
% Arg:
0
7
67
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
0
0
0
20
7
0
0
7
7
14
60
0
% S
% Thr:
7
0
0
0
0
14
0
0
7
0
7
0
7
7
7
% T
% Val:
0
7
0
20
47
7
0
7
0
7
7
60
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _