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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V0A1 All Species: 38.48
Human Site: T250 Identified Species: 76.97
UniProt: Q93050 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93050 NP_001123492.1 837 96413 T250 S L Y P C P E T P Q E R K E M
Chimpanzee Pan troglodytes XP_001165034 837 96375 T250 S L Y P C P E T P Q E R K E M
Rhesus Macaque Macaca mulatta XP_001095161 767 88240 G226 V F I I F F Q G D Q L K N R V
Dog Lupus familis XP_849622 839 96501 T251 S L Y P C P E T P Q E R K E M
Cat Felis silvestris
Mouse Mus musculus Q9Z1G4 839 96482 T257 S L Y P C P E T P Q E R K E M
Rat Rattus norvegicus P25286 838 96309 T250 S L Y P C P E T P Q E R K E M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9I8D0 838 95966 T250 S L Y P C P E T P Q E R K E M
Frog Xenopus laevis Q8AVM5 831 95538 T250 S L Y P C P E T P Q E R K E M
Zebra Danio Brachydanio rerio NP_001018502 839 95617 T250 S L Y P C P E T P Q E R K E M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30628 905 103383 T286 T L Y P C P D T P Q E R R E M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32563 840 95510 S266 N L Y D V D S S N E G R S Q Q
Red Bread Mold Neurospora crassa Q01290 856 97974 H271 E V Y N V D E H S D L R R D Q
Conservation
Percent
Protein Identity: 100 99.8 89.3 97.2 N.A. 95.3 96 N.A. N.A. 92 88.2 83.7 N.A. N.A. N.A. 56.9 N.A.
Protein Similarity: 100 99.8 90.5 98.4 N.A. 97.5 98.3 N.A. N.A. 95.5 94.1 90.9 N.A. N.A. N.A. 70.3 N.A.
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. N.A. N.A. 80 N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. N.A. 100 100 100 N.A. N.A. N.A. 100 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 41.3 41.5
Protein Similarity: N.A. N.A. N.A. N.A. 57.1 60.9
P-Site Identity: N.A. N.A. N.A. N.A. 20 20
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 75 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 17 9 0 9 9 0 0 0 9 0 % D
% Glu: 9 0 0 0 0 0 75 0 0 9 75 0 0 75 0 % E
% Phe: 0 9 0 0 9 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 9 67 0 0 % K
% Leu: 0 84 0 0 0 0 0 0 0 0 17 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75 % M
% Asn: 9 0 0 9 0 0 0 0 9 0 0 0 9 0 0 % N
% Pro: 0 0 0 75 0 75 0 0 75 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 9 0 0 84 0 0 0 9 17 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 92 17 9 0 % R
% Ser: 67 0 0 0 0 0 9 9 9 0 0 0 9 0 0 % S
% Thr: 9 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % T
% Val: 9 9 0 0 17 0 0 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 92 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _