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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LPP All Species: 19.7
Human Site: S227 Identified Species: 36.11
UniProt: Q93052 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93052 NP_005569.1 612 65746 S227 T F N V Q V K S A Q P S P H Y
Chimpanzee Pan troglodytes XP_001159584 680 73450 S295 T F N V Q V K S A Q P S P H Y
Rhesus Macaque Macaca mulatta XP_001104284 416 44041 Q40 S I S V S T Q Q P P K K F A P
Dog Lupus familis XP_850342 615 65837 Q230 N V Q V K S A Q P S S L Y M A
Cat Felis silvestris
Mouse Mus musculus Q8BFW7 613 65872 S228 T F N V Q V K S A Q P S P H Y
Rat Rattus norvegicus Q5XI07 632 68242 S224 A F N V Q V K S A Q P S T H Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512190 613 66056 S228 T F N V Q V K S A Q P S S H F
Chicken Gallus gallus Q5F464 604 65121 F219 S T P S R P T F N V Q V R T A
Frog Xenopus laevis A5H447 663 70707 S279 S P K T V T F S P K S A P H T
Zebra Danio Brachydanio rerio A8DZE6 648 70883 I250 M G Y D Q R H I S P R S S T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396072 477 52619 N101 N I V Y S N I N P P I S I P I
Nematode Worm Caenorhab. elegans Q09476 413 46434 D36 L R R A H I S D R R S Q S R D
Sea Urchin Strong. purpuratus XP_798292 448 48550 S72 N A L P P S G S K G A P P P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.8 66.5 92.5 N.A. 89.4 83.8 N.A. 81.4 78.7 31.8 27 N.A. N.A. 34.6 22 38.2
Protein Similarity: 100 89.8 66.8 93.9 N.A. 92 87.8 N.A. 84 82.6 45.8 41.6 N.A. N.A. 49.8 35.2 46.9
P-Site Identity: 100 100 6.6 6.6 N.A. 100 86.6 N.A. 86.6 0 20 13.3 N.A. N.A. 6.6 0 13.3
P-Site Similarity: 100 100 26.6 13.3 N.A. 100 86.6 N.A. 93.3 13.3 40 20 N.A. N.A. 13.3 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 8 0 0 8 0 39 0 8 8 0 8 16 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 39 0 0 0 0 8 8 0 0 0 0 8 0 8 % F
% Gly: 0 8 0 0 0 0 8 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 8 0 8 0 0 0 0 0 0 47 0 % H
% Ile: 0 16 0 0 0 8 8 8 0 0 8 0 8 0 8 % I
% Lys: 0 0 8 0 8 0 39 0 8 8 8 8 0 0 0 % K
% Leu: 8 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 24 0 39 0 0 8 0 8 8 0 0 0 0 0 0 % N
% Pro: 0 8 8 8 8 8 0 0 31 24 39 8 39 16 8 % P
% Gln: 0 0 8 0 47 0 8 16 0 39 8 8 0 0 0 % Q
% Arg: 0 8 8 0 8 8 0 0 8 8 8 0 8 8 0 % R
% Ser: 24 0 8 8 16 16 8 54 8 8 24 54 24 0 0 % S
% Thr: 31 8 0 8 0 16 8 0 0 0 0 0 8 16 24 % T
% Val: 0 8 8 54 8 39 0 0 0 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 8 0 0 0 0 0 0 0 0 8 0 31 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _