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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LPP All Species: 17.58
Human Site: S231 Identified Species: 32.22
UniProt: Q93052 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93052 NP_005569.1 612 65746 S231 Q V K S A Q P S P H Y M A A P
Chimpanzee Pan troglodytes XP_001159584 680 73450 S299 Q V K S A Q P S P H Y M A A P
Rhesus Macaque Macaca mulatta XP_001104284 416 44041 K44 S T Q Q P P K K F A P V V A P
Dog Lupus familis XP_850342 615 65837 L234 K S A Q P S S L Y M A A P S S
Cat Felis silvestris
Mouse Mus musculus Q8BFW7 613 65872 S232 Q V K S A Q P S P H Y M A G P
Rat Rattus norvegicus Q5XI07 632 68242 S228 Q V K S A Q P S T H Y M T G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512190 613 66056 S232 Q V K S A Q P S S H F M P A P
Chicken Gallus gallus Q5F464 604 65121 V223 R P T F N V Q V R T A Q P S P
Frog Xenopus laevis A5H447 663 70707 A283 V T F S P K S A P H T F M P K
Zebra Danio Brachydanio rerio A8DZE6 648 70883 S254 Q R H I S P R S S T T S P R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396072 477 52619 S105 S N I N P P I S I P I N K T T
Nematode Worm Caenorhab. elegans Q09476 413 46434 Q40 H I S D R R S Q S R D D F E Q
Sea Urchin Strong. purpuratus XP_798292 448 48550 P76 P S G S K G A P P P T L P K P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.8 66.5 92.5 N.A. 89.4 83.8 N.A. 81.4 78.7 31.8 27 N.A. N.A. 34.6 22 38.2
Protein Similarity: 100 89.8 66.8 93.9 N.A. 92 87.8 N.A. 84 82.6 45.8 41.6 N.A. N.A. 49.8 35.2 46.9
P-Site Identity: 100 100 13.3 0 N.A. 93.3 73.3 N.A. 80 6.6 20 13.3 N.A. N.A. 6.6 0 20
P-Site Similarity: 100 100 26.6 13.3 N.A. 93.3 73.3 N.A. 86.6 20 33.3 20 N.A. N.A. 13.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 39 0 8 8 0 8 16 8 24 31 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 8 8 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 8 8 0 0 0 0 8 0 8 8 8 0 0 % F
% Gly: 0 0 8 0 0 8 0 0 0 0 0 0 0 16 0 % G
% His: 8 0 8 0 0 0 0 0 0 47 0 0 0 0 0 % H
% Ile: 0 8 8 8 0 0 8 0 8 0 8 0 0 0 0 % I
% Lys: 8 0 39 0 8 8 8 8 0 0 0 0 8 8 8 % K
% Leu: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 39 8 0 0 % M
% Asn: 0 8 0 8 8 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 8 8 0 0 31 24 39 8 39 16 8 0 39 8 54 % P
% Gln: 47 0 8 16 0 39 8 8 0 0 0 8 0 0 8 % Q
% Arg: 8 8 0 0 8 8 8 0 8 8 0 0 0 8 0 % R
% Ser: 16 16 8 54 8 8 24 54 24 0 0 8 0 16 24 % S
% Thr: 0 16 8 0 0 0 0 0 8 16 24 0 8 8 8 % T
% Val: 8 39 0 0 0 8 0 8 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 31 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _