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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LPP All Species: 27.58
Human Site: S577 Identified Species: 50.56
UniProt: Q93052 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93052 NP_005569.1 612 65746 S577 E D C G G L L S E G D N Q G C
Chimpanzee Pan troglodytes XP_001159584 680 73450 S645 E D C G G L L S E G D N Q G C
Rhesus Macaque Macaca mulatta XP_001104284 416 44041 S382 H T G Q L G P S S V P P S L R
Dog Lupus familis XP_850342 615 65837 S580 E D C G G L L S E G D N Q G C
Cat Felis silvestris
Mouse Mus musculus Q8BFW7 613 65872 S578 E D C G G L L S E G D N Q G C
Rat Rattus norvegicus Q5XI07 632 68242 S597 E D C G G L L S E G D N Q G C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512190 613 66056 S578 E D C G G L L S E G D N Q G C
Chicken Gallus gallus Q5F464 604 65121 S569 E D C G G L L S E G D N Q G C
Frog Xenopus laevis A5H447 663 70707 G629 C Y K C E D C G C P L S I E A
Zebra Danio Brachydanio rerio A8DZE6 648 70883 N605 E D C G L Q L N D E E G H R C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396072 477 52619 D443 C G L I L S S D S E G R G C Y
Nematode Worm Caenorhab. elegans Q09476 413 46434 C379 F H P E H F R C S Y C N H Q L
Sea Urchin Strong. purpuratus XP_798292 448 48550 C414 H C Y K C E D C G V L L S S E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.8 66.5 92.5 N.A. 89.4 83.8 N.A. 81.4 78.7 31.8 27 N.A. N.A. 34.6 22 38.2
Protein Similarity: 100 89.8 66.8 93.9 N.A. 92 87.8 N.A. 84 82.6 45.8 41.6 N.A. N.A. 49.8 35.2 46.9
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 100 100 0 40 N.A. N.A. 0 6.6 0
P-Site Similarity: 100 100 6.6 100 N.A. 100 100 N.A. 100 100 6.6 60 N.A. N.A. 0 6.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 16 8 62 8 8 0 8 16 8 0 8 0 0 8 62 % C
% Asp: 0 62 0 0 0 8 8 8 8 0 54 0 0 0 0 % D
% Glu: 62 0 0 8 8 8 0 0 54 16 8 0 0 8 8 % E
% Phe: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 8 62 54 8 0 8 8 54 8 8 8 54 0 % G
% His: 16 8 0 0 8 0 0 0 0 0 0 0 16 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 24 54 62 0 0 0 16 8 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 62 0 0 0 % N
% Pro: 0 0 8 0 0 0 8 0 0 8 8 8 0 0 0 % P
% Gln: 0 0 0 8 0 8 0 0 0 0 0 0 54 8 0 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 8 0 8 8 % R
% Ser: 0 0 0 0 0 8 8 62 24 0 0 8 16 8 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 0 0 0 8 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _