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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LPP All Species: 6.67
Human Site: T333 Identified Species: 12.22
UniProt: Q93052 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93052 NP_005569.1 612 65746 T333 W K R E P G Y T P P G A G N Q
Chimpanzee Pan troglodytes XP_001159584 680 73450 T401 W K R E P G Y T P P G A G N Q
Rhesus Macaque Macaca mulatta XP_001104284 416 44041 S146 K P R P P Q S S T G S T A S P
Dog Lupus familis XP_850342 615 65837 P336 W K R E Q G Y P P F G T G N Q
Cat Felis silvestris
Mouse Mus musculus Q8BFW7 613 65872 A334 W K R E A A Y A P P A S G N Q
Rat Rattus norvegicus Q5XI07 632 68242 A330 W K R E P G Y A A P G A G N Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512190 613 66056 A334 W K P E P T Y A P P V A P P Q
Chicken Gallus gallus Q5F464 604 65121 P325 Q S T W K V E P A Y P S S N T
Frog Xenopus laevis A5H447 663 70707 R385 G P Q T E S G R S P G A Q S T
Zebra Danio Brachydanio rerio A8DZE6 648 70883 L356 D F T E P N G L H N N R V H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396072 477 52619 S207 N D I Y G P S S Q S S S T Y E
Nematode Worm Caenorhab. elegans Q09476 413 46434 R142 S D V R S N G R S P S R D P L
Sea Urchin Strong. purpuratus XP_798292 448 48550 R178 P A V Q P G Y R Q P S Y R Q Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.8 66.5 92.5 N.A. 89.4 83.8 N.A. 81.4 78.7 31.8 27 N.A. N.A. 34.6 22 38.2
Protein Similarity: 100 89.8 66.8 93.9 N.A. 92 87.8 N.A. 84 82.6 45.8 41.6 N.A. N.A. 49.8 35.2 46.9
P-Site Identity: 100 100 13.3 73.3 N.A. 66.6 86.6 N.A. 60 6.6 20 13.3 N.A. N.A. 0 6.6 33.3
P-Site Similarity: 100 100 26.6 73.3 N.A. 73.3 86.6 N.A. 60 13.3 33.3 20 N.A. N.A. 20 6.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 8 0 24 16 0 8 39 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 16 0 0 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 0 0 0 54 8 0 8 0 0 0 0 0 0 0 8 % E
% Phe: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 8 0 0 0 8 39 24 0 0 8 39 0 39 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 47 0 0 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 16 0 0 0 8 8 0 0 47 0 % N
% Pro: 8 16 8 8 54 8 0 16 39 62 8 0 8 16 8 % P
% Gln: 8 0 8 8 8 8 0 0 16 0 0 0 8 8 54 % Q
% Arg: 0 0 47 8 0 0 0 24 0 0 0 16 8 0 0 % R
% Ser: 8 8 0 0 8 8 16 16 16 8 31 24 8 16 0 % S
% Thr: 0 0 16 8 0 8 0 16 8 0 0 16 8 0 16 % T
% Val: 0 0 16 0 0 8 0 0 0 0 8 0 8 0 0 % V
% Trp: 47 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 54 0 0 8 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _