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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LPP All Species: 16.06
Human Site: Y251 Identified Species: 29.44
UniProt: Q93052 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q93052 NP_005569.1 612 65746 Y251 Y G S G P Q G Y N T Q P V P V
Chimpanzee Pan troglodytes XP_001159584 680 73450 Y319 Y G S G P Q G Y N T Q P V P V
Rhesus Macaque Macaca mulatta XP_001104284 416 44041 E64 P Y K Q P G G E G D F L P P P
Dog Lupus familis XP_850342 615 65837 Y254 T G P G P Q G Y N T Q P V S I
Cat Felis silvestris
Mouse Mus musculus Q8BFW7 613 65872 Y252 Y G P G P R G Y N N Q P V P V
Rat Rattus norvegicus Q5XI07 632 68242 Y248 Y G P G S R S Y N T Q Q V P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512190 613 66056 T252 F N Q G L S Q T Y G P Q T A R
Chicken Gallus gallus Q5F464 604 65121 G243 G P Q P T H Y G S L G P G Q P
Frog Xenopus laevis A5H447 663 70707 E303 T Y P Q K T T E P P A E A S Q
Zebra Danio Brachydanio rerio A8DZE6 648 70883 H274 R F T P A G G H D P E S A A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396072 477 52619 W125 I I Y S N I Q W N S K P E N T
Nematode Worm Caenorhab. elegans Q09476 413 46434 V60 G N L N T Q S V S N G N I T T
Sea Urchin Strong. purpuratus XP_798292 448 48550 P96 P T A A A K G P P P M P P P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.8 66.5 92.5 N.A. 89.4 83.8 N.A. 81.4 78.7 31.8 27 N.A. N.A. 34.6 22 38.2
Protein Similarity: 100 89.8 66.8 93.9 N.A. 92 87.8 N.A. 84 82.6 45.8 41.6 N.A. N.A. 49.8 35.2 46.9
P-Site Identity: 100 100 20 73.3 N.A. 80 60 N.A. 6.6 6.6 0 13.3 N.A. N.A. 13.3 6.6 20
P-Site Similarity: 100 100 20 80 N.A. 86.6 73.3 N.A. 13.3 13.3 0 40 N.A. N.A. 33.3 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 16 0 0 0 0 0 8 0 16 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 16 0 0 8 8 8 0 0 % E
% Phe: 8 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 16 39 0 47 0 16 54 8 8 8 16 0 8 0 0 % G
% His: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 8 0 0 0 0 0 0 8 0 8 % I
% Lys: 0 0 8 0 8 8 0 0 0 0 8 0 0 0 8 % K
% Leu: 0 0 8 0 8 0 0 0 0 8 0 8 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 16 0 8 8 0 0 0 47 16 0 8 0 8 0 % N
% Pro: 16 8 31 16 39 0 0 8 16 24 8 54 16 47 16 % P
% Gln: 0 0 16 16 0 31 16 0 0 0 39 16 0 8 8 % Q
% Arg: 8 0 0 0 0 16 0 0 0 0 0 0 0 0 8 % R
% Ser: 0 0 16 8 8 8 16 0 16 8 0 8 0 16 0 % S
% Thr: 16 8 8 0 16 8 8 8 0 31 0 0 8 8 16 % T
% Val: 0 0 0 0 0 0 0 8 0 0 0 0 39 0 31 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 31 16 8 0 0 0 8 39 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _